Exploring the transcriptome of resident spinal microglia after collagen antibody–induced arthritis
Sign Up to like & getrecommendations! Published in 2019 at "Pain"
DOI: 10.1097/j.pain.0000000000001394
Abstract: Abstract Recent studies have suggested a sexually dimorphic role of spinal glial cells in the maintenance of mechanical hypersensitivity in rodent models of chronic pain. We have used the collagen antibody–induced arthritis (CAIA) mouse model… read more here.
Keywords: induced arthritis; antibody induced; collagen antibody;
Antiphospholipid antibody‐induced trophoblast responses are differentially modulated by viral dsRNA and viral ssRNA
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13516
Abstract: Women with antiphospholipid antibodies (aPL) are at increased risk for pregnancy loss and preeclampsia. aPL target the trophoblast and induce a pro‐inflammatory, anti‐angiogenic and anti‐migratory profile. Since infection during pregnancy can increase the risk for… read more here.
Keywords: differentially modulated; induced trophoblast; antiphospholipid antibody; responses differentially ... See more keywords
Comparative analysis of human leucocyte antigen between idiopathic and anti‐PD‐1 antibody induced isolated adrenocorticotropic hormone deficiency: A pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Endocrinology"
DOI: 10.1111/cen.14082
Abstract: Adult‐onset idiopathic isolated adrenocorticotropic hormone deficiency (id‐IAD) is a rare disease with unknown aetiology. Recently, numerous cases of anti‐PD‐1 antibody‐induced IAD (PD1‐IAD) have been reported, but the clinical course, predictive factors and relationship to id‐IAD… read more here.
Keywords: anti antibody; human leucocyte; antibody induced; adrenocorticotropic hormone ... See more keywords
Tramadol/paracetamol treatment attenuates the development of collagen antibody-induced arthritis and interferes with prednisolone treatment in mice.
Sign Up to like & getrecommendations! Published in 2023 at "Laboratory animals"
DOI: 10.1177/00236772231166029
Abstract: The collagen antibody-induced arthritis (CAIA) model is highly effective in inducing arthritis, making it an attractive model for screening therapeutic compounds such as glucocorticoids (GCs). The severity of discomfort in this model makes it desirable… read more here.
Keywords: arthritis; collagen antibody; model; mice ... See more keywords
Evaluation of Plasma-Derived FVII Efficacy for the Treatment of Bleeding in a Murine Model of Hemophilia a
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.1070.1070
Abstract: Background Recombinant human activated factor VII (rhFVIIa) has been used successfully to treat hemophilic patients with neutralizing antibodies to FVIII or FIX. High doses of FVIIa are known to be effective in opposing bleeding in… read more here.
Keywords: factor vii; antibody induced; model; mice ... See more keywords
PD-1 Antibody-induced Guillain-Barré Syndrome in a Patient with Metastatic Melanoma.
Sign Up to like & getrecommendations! Published in 2017 at "Acta dermato-venereologica"
DOI: 10.2340/00015555-2548
Abstract: Guillain-Barré syndrome (GBS) presents as acute inflammatory demyelinating polyneuropathy, which leads to rapid-onset muscle weakness classically caused by immune-mediated damage to the peripheral nervous system. We report here a case of GBS occurring during treatment… read more here.
Keywords: syndrome patient; guillain barr; antibody induced; induced guillain ... See more keywords
A mutated factor X activatable by thrombin corrects bleedings in vivo in a rabbit model of antibody-induced hemophilia A.
Sign Up to like & getrecommendations! Published in 2019 at "Haematologica"
DOI: 10.3324/haematol.2019.219865
Abstract: Rendering coagulation factor X sensitive to thrombin was proposed as a strategy that can bypass the need for factor VIII. In this paper, this non-replacement strategy was evaluated in vitro and in vivo in its… read more here.
Keywords: antibody induced; model; rabbit; factor ... See more keywords