APOE Antibody Inhibits Aβ‐Associated Tau Seeding and Spreading in a Mouse Model
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26351
Abstract: APOE is the strongest genetic factor for late‐onset Alzheimer's disease (AD). A specific conformation of the ApoE protein is present in amyloid‐β (Aβ) containing plaques. Immunotherapy targeting ApoE in plaques reduces brain Aβ deposits in… read more here.
Keywords: inhibits associated; antibody inhibits; apoe antibody; tau seeding ... See more keywords
A single-domain antibody inhibits SFTSV and mitigates virus-induced pathogenesis in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.136855
Abstract: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne bunyavirus that recently emerged in East Asian countries. SFTS is characterized by high fever, thrombocytopenia, leukopenia, multiorgan failure, and hemorrhage with case fatality rates… read more here.
Keywords: vivo; antibody inhibits; single domain; inhibits sftsv ... See more keywords