Shaping Polyclonal Responses via Antigen-Mediated Antibody Interference
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101568
Abstract: Summary Broadly neutralizing antibodies (bnAbs) recognize conserved features of rapidly mutating pathogens and confer universal protection, but they emerge rarely in natural infection. Increasing evidence indicates that seemingly passive antibodies may interfere with natural selection… read more here.
Keywords: polyclonal responses; interference; antibody interference; antigen mediated ... See more keywords
Therapeutic Monoclonal Antibody Interference in Monoclonal Gammopathy Monitoring: a Denosumab Experience.
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac129
Abstract: A 73-year-old woman was diagnosed with a lambda light chain myeloma. A follow-up immunofixation electrophoresis showed a monoclonal immunoglobulin (Ig)G kappa in addition to the regular lambda band. A monoclonal antibody therapy interference was suspected… read more here.
Keywords: denosumab; monoclonal antibody; therapeutic monoclonal; interference ... See more keywords
Mitigation of therapeutic anti‐CD38 antibody interference with fab fragments: How well does it perform?
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DOI: 10.1111/trf.17253
Abstract: Administration of anti‐CD38 antibodies is a state‐of‐the‐art therapy for patients diagnosed with multiple myeloma (MM). However, this treatment frequently leads to pan‐agglutination of red blood cells (RBCs) in patients' serological testing making accurate blood typing… read more here.
Keywords: anti cd38; cd38 antibody; interference fab; antibody interference ... See more keywords