Successful use of nonantigen‐specific immunoadsorption with antihuman Ig‐columns in kidney graft antibody‐mediated rejection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21779
Abstract: Nonantigen‐specific immunoadsorption (IA) has proven to be effective in acute antibody‐mediated rejection (aAMR). However, there is a lack of solid studies evaluating the safety and efficacy of IA with antihuman Ig‐columns in aAMR. For chronic‐active… read more here.
Keywords: specific immunoadsorption; antihuman columns; mediated rejection; antibody mediated ... See more keywords
In Vivo Kidney Allograft Endothelial Specific Scavengers for On-Site Inflammation Reduction under Antibody-Mediated Rejection.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202106746
Abstract: Kidney transplantation is the most effective therapy for patients with end-stage renal disease. However, antibody-mediated rejection (ABMR) threatens long-term survival of renal grafts. Although ABMR can be controlled by donor-specific antibody clearance and B- or… read more here.
Keywords: antibody; mediated rejection; specific scavengers; kidney ... See more keywords
Rabbit anti-human thymocyte immunoglobulin for the rescue treatment of chronic antibody-mediated rejection after pediatric kidney transplantation
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3725-1
Abstract: BackgroundChronic antibody-mediated rejection (cAMR) is the leading cause of late kidney graft loss, but current therapies are often ineffective. Rabbit anti-human thymocyte immunoglobulin (rATG) may be helpful, but its use is virtually undocumented.MethodsData were analyzed… read more here.
Keywords: mediated rejection; human thymocyte; anti human; antibody mediated ... See more keywords
Successful management of antibody-mediated rejection after cardiac transplantation in a patient supported by a left ventricular assist device for more than 3 years
Sign Up to like & getrecommendations! Published in 2017 at "General Thoracic and Cardiovascular Surgery"
DOI: 10.1007/s11748-017-0763-3
Abstract: Due to donor shortage, patients with refractory heart failure need to be supported on mechanical circulatory support (MCS). Critically, patients undergo several deployments of MCS in stages inevitably requiring blood products transfusion. MCSs per se… read more here.
Keywords: mediated rejection; antibody; transplantation; antibody mediated ... See more keywords
Non-invasive screening for sub-clinical antibody-mediated rejection as a new tool for indication of kidney allograft biopsy
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.07.033
Abstract: Antibody-mediated rejection (ABMR) is nowadays the major probdiagnosis) and inspected arbitrarily chosen thresholds, which could lem for long-term kidney allograft survival. ABMR frequently takes a continuous and fluctuating course. It often occurs sub-clinically, and abnormal… read more here.
Keywords: mediated rejection; rejection; allograft; antibody mediated ... See more keywords
Management of Antibody Mediated Rejection (AMR) in Heart Transplant Patients: The Real World in a French Single Center Treating All Pathological AMR
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.839
Abstract: Purpose There is no consensus for the treatment of antibody mediated rejection (AMR) in heart transplant patients (HTP), only expert recommendation with a grey zone in patients without graft dysfunction. The purpose of the study… read more here.
Keywords: heart; dysfunction; rejection amr; graft dysfunction ... See more keywords
P219 Antibody-mediated rejection (AMR) not detected at autopsy in infant with ABO incompatible (ABOI) cardiac transplant despite increased levels of C1Q+ donor-specific antibodies (DSA) and possible previously-detected antibody-mediated rejection
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.279
Abstract: A 4 mo male with complex congenital heart disease underwent ABOi transplantation (tx) (patient O+, donor AB+). Patient received multiple transfusions, but DSA were absent (PRA 0% pre-tx). Flow XM were negative. Patient underwent intra-operative plasma… read more here.
Keywords: mediated rejection; acr; rejection; amr ... See more keywords
P029 A case of acute tubular necrosis, antibody mediated rejection, or both
Sign Up to like & getrecommendations! Published in 2018 at "Human Immunology"
DOI: 10.1016/j.humimm.2018.07.087
Abstract: We investigated the cause of impaired allograft function in the case of biopsy-proven Acute Tubular Necrosis (ATN) with C4d deposits, in the absence of other Antibody Mediated Rejection (AMR) features. ATN, an acute injury of… read more here.
Keywords: acute tubular; mediated rejection; rejection; case ... See more keywords
Regulation of T- and B-cell interactions determines the clinical phenotype associated with donor-specific antibodies.
Sign Up to like & getrecommendations! Published in 2022 at "Kidney international"
DOI: 10.1016/j.kint.2022.02.020
Abstract: The cellular mechanisms that regulate donor-specific antibody formation and antibody-mediated rejection remain unknown. In this issue, Louis et al. report that specific T-regulatory cell and B-regulatory transitional cell subsets are concomitantly diminished in patients with donor-specific… read more here.
Keywords: donor specific; cell; antibody; specific antibody ... See more keywords
Eculizumab for Prevention of Antibody-Mediated Rejection in Blood Group-Incompatible Renal Transplantation.
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2017.12.015
Abstract: Antibody-mediated rejection (AMR) is one of the leading causes of allograft failure especially in patients undergoing ABO-incompatible (ABOi) renal transplantation. We hypothesized that complement inhibition with eculizumab, a C5 inhibitor, would protect against AMR and… read more here.
Keywords: antibody mediated; transplantation; mediated rejection; renal transplantation ... See more keywords
Outcomes of Prolonged Treatment With Intravenous Immunoglobulin Infusions for Acute Antibody-mediated Rejection in Kidney Transplant Recipients.
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.02.110
Abstract: BACKGROUND Treatment of antibody-mediated rejection (AMR) is one of the main problems after kidney transplantation (KTx). The results of intensive AMR treatment with plasmapheresis (PF) and repeated infusions of intravenous immunoglobulin (IVIg) are presented. METHODS… read more here.
Keywords: intravenous immunoglobulin; mediated rejection; range; treatment ... See more keywords