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Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202101376
Abstract: Antibodies are widely used as recognition elements in sensing and therapy, but they suffer from poor stability, long discovery time, and high cost. Herein, a facile approach to create antibody mimics with flexible recognition phases…
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Keywords:
tpa antibody;
pathogenic bacteria;
recognition;
inactivation ... See more keywords
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Published in 2017 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2017.07.001
Abstract: The rational/structure-based design and/or combinatorial development of molecules capable of selectively binding to a protein, represents a promising strategy for a range of biomedical applications, in particular the inhibition of disease-associated protein-ligand interactions. The design…
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Keywords:
protein;
antibody;
ligand interactions;
antibody mimics ... See more keywords
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Published in 2020 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.0c00428
Abstract: Molecularly imprinted polymers (MIPs) are tailor-made chemical receptors that recognize and bind target molecules with a high affinity and selectivity. MIPs came into the spotlight in 1993 when they were dubbed "antibody mimics," and ever…
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Keywords:
polymers antibody;
bioimaging therapy;
antibody mimics;
molecularly imprinted ... See more keywords