Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma
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DOI: 10.1186/s40478-018-0583-4
Abstract: Glioblastoma (GB) is the most frequent primary brain tumor in adults with a dismal prognosis despite aggressive treatment including surgical resection, radiotherapy and chemotherapy with the alkylating agent temozolomide. Thus far, the successful implementation of… read more here.
Keywords: mtorc1 signaling; glioblastoma; antibody nimotuzumab; akt mtorc1 ... See more keywords