Targeted siRNA nanocarrier: a platform technology for cancer treatment
Sign Up to like & getrecommendations! Published in 2022 at "Oncogene"
DOI: 10.1038/s41388-022-02241-w
Abstract: The small arginine-rich protein protamine condenses complete genomic DNA into the sperm head. Here, we applied its high RNA binding capacity for spontaneous electrostatic assembly of therapeutic nanoparticles decorated with tumour-cell-specific antibodies for efficiently targeting… read more here.
Keywords: cancer; antibody protamine; treatment; platform technology ... See more keywords