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Published in 2019 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2019.107315
Abstract: Abstract Traditional purification platforms for monoclonal antibodies (mAbs) rely heavily on 3–4 step chromatographic operations with protein A affinity chromatography as the essential antibody capture approach. In this study, we applied for the first time…
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Keywords:
purification;
antibody purification;
chromatin directed;
antibody ... See more keywords
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Published in 2019 at "mAbs"
DOI: 10.1080/19420862.2019.1565749
Abstract: ABSTRACT We introduce a new concept and potentially general platform for antibody (Ab) purification that does not rely on chromatography or specific ligands (e.g., Protein A); rather, it makes use of detergent aggregates capable of…
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Keywords:
platform antibody;
antibody purification;
engineered micelles;
general platform ... See more keywords