A broadly neutralizing antibody recognizes a unique epitope with a signature motif common across coronaviruses
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-63101-1
Abstract: Cross-reactive antibodies targeting multiple epitopes have been identified in Sarbecoviruses, but the precise molecular mechanism(s) behind the crossreactivity remain poorly understood. Here, we isolate 3D1, a broadly neutralizing antibody (bnAb) derived from a human combinatorial… read more here.
Keywords: antibody recognizes; antibody; broadly neutralizing; neutralizing antibody ... See more keywords
Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-02199-7
Abstract: The terminal galactose residues of N- and O-glycans in animal glycoproteins are often sialylated and/or fucosylated, but sulfation, such as 3-O-sulfated galactose (3-O-SGal), represents an additional, but poorly understood modification. To this end, we have… read more here.
Keywords: novel lamprey; terminal sulfated; lamprey antibody; sulfated galactose ... See more keywords
Patient-derived antibody recognizes a unique CD43 epitope expressed on all AML and has antileukemia activity in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Blood advances"
DOI: 10.1182/bloodadvances.2017008342
Abstract: Immunotherapy has proven beneficial in many hematologic and nonhematologic malignancies, but immunotherapy for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) is hampered by the lack of tumor-specific targets. We took advantage of the tumor-immunotherapeutic… read more here.
Keywords: antibody; unique cd43; recognizes unique; antibody recognizes ... See more keywords
Development and characterization of an antibody that recognizes influenza virus N1 neuraminidases
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DOI: 10.1371/journal.pone.0302865
Abstract: Influenza A viruses (IAVs) continue to pose a huge threat to public health, and their prevention and treatment remain major international issues. Neuraminidase (NA) is the second most abundant surface glycoprotein on influenza viruses, and… read more here.
Keywords: development characterization; characterization antibody; antibody recognizes; antibody ... See more keywords
A Novel FLI1 Monoclonal Antibody Which Recognizes EWS::FLI1 with High Affinity Is Useful for Detecting Ewing Sarcoma
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DOI: 10.3390/antib14040097
Abstract: Background: Ewing sarcoma (ES) is a rare tumor that affects children, adolescents, and young adults. ES is associated with high morbidity in all patients and high mortality for those who present with metastatic disease. A… read more here.
Keywords: monoclonal antibody; high affinity; antibody recognizes; antibody ... See more keywords