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Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2016.10.018
Abstract: HIGHLIGHTSChinese IVIgs express a large range of antibody reactivities against E. coli.Each IVIg preparation has its own distinct antibody repertoire.The target antigens are high conserved proteins in pathogenic microorganisms. ABSTRACT Intravenous immunoglobulin (IVIg) is produced…
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Keywords:
escherichia coli;
antibody repertoire;
antibody;
igg antibody ... See more keywords
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Published in 2019 at "Life sciences in space research"
DOI: 10.1016/j.lssr.2019.06.001
Abstract: Spaceflight is known to impact the immune system in multiple ways. However, its effect on the antibody repertoire, especially in response to challenge, has not been well characterized. The development of the repertoire has multiple…
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Keywords:
cpg;
bone marrow;
antibody repertoire;
gene ... See more keywords
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Published in 2018 at "Genome Medicine"
DOI: 10.1186/s13073-018-0542-5
Abstract: Existing methods for paired antibody heavy- and light-chain repertoire sequencing rely on specialized equipment and are limited by their commercial availability and high costs. Here, we report a novel simple and cost-effective emulsion-based single-cell paired…
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Keywords:
repertoire;
antibody repertoire;
repertoire sequencing;
light chain ... See more keywords
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Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0210284
Abstract: Spaceflight affects the immune system, but the effects on the antibody repertoire, responsible for humoral immunity, has not been well explored. In particular, the complex gene assembly and expression process; including mutations, might make this…
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Keywords:
skeletal unloading;
antibody repertoire;
repertoire;
gene ... See more keywords
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Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00254
Abstract: Antibody repertoire sequencing provides a molecular fingerprint of current and past pathogens encountered by the immune system. Most repertoire studies in humans require measuring the B cell response in the blood, resulting in a large…
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Keywords:
igm antibody;
antibody repertoire;
infection;
repertoire ... See more keywords
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Published in 2022 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2022062
Abstract: High-throughput sequencing for B cell receptor (BCR) repertoire provides useful insights for the adaptive immune system. With the continuous development of the BCR-seq technology, many efforts have been made to develop methods for analyzing the…
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Keywords:
antibody repertoire;
bcr repertoire;
analysis;
repertoire ... See more keywords