SARS-CoV-2 Antibody Responses in Infection-Naive or Previously Infected Individuals After 1 and 2 Doses of the BNT162b2 Vaccine
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.19741
Abstract: This cohort study examines antibody responses in infection-naive and previously infected individuals after 1 and 2 doses of the BNT162b2 vaccine. read more here.
Keywords: infection naive; responses infection; infected individuals; previously infected ... See more keywords
The unexpected contribution of conventional type 1 dendritic cells in driving antibody responses
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DOI: 10.1002/eji.202149658
Abstract: Antibodies are hallmarks of most effective vaccines. For successful T‐dependent antibody responses, conventional dendritic cells (cDC) have been largely attributed the role of priming T cells. By contrast, follicular dendritic cells and macrophages have been… read more here.
Keywords: present native; antigen; dendritic cells; native antigen ... See more keywords
Antibody responses against SARS‐CoV‐2 in COVID‐19 patients
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26241
Abstract: Abstract The emerging coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has become a global pandemic, and brings formidable challenges to public health, society and the economy worldwide. Currently, the… read more here.
Keywords: covid patients; cov covid; virology; responses sars ... See more keywords
Antibody responses to SARS‐CoV‐2 in healthy individuals returning to Shenzhen
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DOI: 10.1002/jmv.26355
Abstract: To verify reliability of antibody detection and investigate population immunity to severe acute respiratory syndrome‐related coronavirus 2 (SARS‐CoV‐2) in the local Chinese population. A cross‐sectional study was conducted in Shenzhen to detect anti‐coronavirus antibodies including,… read more here.
Keywords: healthy individuals; antibody; shenzhen; sars cov ... See more keywords
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2
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DOI: 10.1016/j.cell.2020.10.043
Abstract: A safe, effective, and scalable vaccine is needed to halt the ongoing SARS-CoV-2 pandemic. We describe the structure-based design of self-assembling protein nanoparticle immunogens that elicit potent and protective antibody responses against SARS-CoV-2 in mice.… read more here.
Keywords: protein nanoparticle; nanoparticle; nanoparticle vaccines; sars cov ... See more keywords
SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses
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DOI: 10.1016/j.cell.2022.01.011
Abstract: Although infections among vaccinated individuals lead to milder COVID-19 symptoms relative to unvaccinated subjects, the specificity and durability of antibody responses elicited by breakthrough cases remain unknown. Here, we demonstrate that breakthrough infections induce serum… read more here.
Keywords: sars cov; cov breakthrough; neutralizing antibody; antibody ... See more keywords
c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses.
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DOI: 10.1016/j.celrep.2017.03.060
Abstract: Humoral immune responses are tailored to the invading pathogen through regulation of key transcription factors and their networks. This is critical to establishing effective antibody-mediated responses, yet it is unknown how B cells integrate pathogen-induced signals… read more here.
Keywords: antibody; program; myb regulates; differentiation ... See more keywords
Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines.
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DOI: 10.1016/j.celrep.2020.02.061
Abstract: Rational immunogen design aims to focus antibody responses to vulnerable sites on primary antigens. Given the size of these antigens, there is, however, potential for eliciting unwanted, off-target responses. Here, we use our electron microscopy… read more here.
Keywords: non human; microscopy; antibody; human primates ... See more keywords
What do we know about the antibody responses to SARS-CoV-2?
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DOI: 10.1016/j.imbio.2021.152054
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However,… read more here.
Keywords: responses sars; antibody; sars cov; know antibody ... See more keywords
Mechanisms underpinning poor antibody responses to vaccines in ageing.
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DOI: 10.1016/j.imlet.2021.11.001
Abstract: Vaccines are a highly effective intervention for conferring protection against infections and reducing the associated morbidity and mortality in vaccinated individuals. However, ageing is often associated with a functional decline in the immune system that… read more here.
Keywords: antibody; mechanisms underpinning; poor antibody; responses vaccines ... See more keywords
A family matter: Anti-viral antibody responses.
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DOI: 10.1016/j.immuni.2021.12.008
Abstract: The immune response is an amalgam of heritable and non-heritable effects, although the contribution of each is generally unknown. In this issue of Immunity, Venkataraman et al. report heritable traits that govern anti-viral antibody epitope specificity… read more here.
Keywords: viral antibody; anti viral; family matter; matter anti ... See more keywords