The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta
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DOI: 10.1080/19420862.2022.2068212
Abstract: ABSTRACT The human adaptive immune response enables the targeting of epitopes on pathogens with high specificity. Infection with a pathogen induces somatic hyper-mutation and B-cell selection processes that govern the shape and diversity of the… read more here.
Keywords: antibody sequence; sequence space; human antibody; sequence ... See more keywords