Variable Domain N-Linked Glycans Acquired During Antigen-Specific Immune Responses Can Contribute to Immunoglobulin G Antibody Stability
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00740
Abstract: Immunoglobulin G (IgG) can contain N-linked glycans in the variable domains, the so-called Fab glycans, in addition to the Fc glycans in the CH2 domains. These Fab glycans are acquired following introduction of N-glycosylation sites… read more here.
Keywords: antibody stability; linked glycans; fab glycans; antibody ... See more keywords
Simultaneous Maturation of Single Chain Antibody Stability and Affinity by CHO Cell Display
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DOI: 10.3390/bioengineering9080360
Abstract: Antibody stability and affinity are two important features of its applications in therapy and diagnosis. Antibody display technologies such as yeast and bacterial displays have been successfully used for improving both affinity and stability. Although… read more here.
Keywords: antibody stability; affinity; stability affinity; cell display ... See more keywords