Antibody Therapies Targeting Complex Membrane Proteins
Sign Up to like & getrecommendations! Published in 2021 at "Engineering"
DOI: 10.1016/j.eng.2020.11.013
Abstract: Abstract In analyses of protein families that may serve as drug targets, membrane-associated G-protein-coupled receptors (GPCRs) dominate, followed by ion channels, transporters, and—to a lesser extent—membrane-bound enzymes. However, various challenges put such membrane proteins among… read more here.
Keywords: membrane proteins; antibody therapies; membrane; therapies targeting ... See more keywords
Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19
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DOI: 10.1016/j.jconrel.2020.11.057
Abstract: COVID-19, the disease caused by infection with SARS-CoV-2, requires urgent development of therapeutic interventions. Due to their safety, specificity, and potential for rapid advancement into the clinic, monoclonal antibodies (mAbs) represent a highly promising class… read more here.
Keywords: challenges monoclonal; antibody therapies; learning past; failures challenges ... See more keywords
Antibody therapies for the prevention and treatment of viral infections
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DOI: 10.1038/s41541-017-0019-3
Abstract: Antibodies are an important component in host immune responses to viral pathogens. Because of their unique maturation process, antibodies can evolve to be highly specific to viral antigens. Physicians and researchers have been relying on… read more here.
Keywords: therapies prevention; antibody therapies; monoclonal antibodies; viral infections ... See more keywords
Monoclonal antibody therapies in the management of SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2030310
Abstract: ABSTRACT Introduction Neutralizing antibodies (NAbs) that target key domains of the spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may have therapeutic value because of their specificity. Depending on the targeted epitope, single… read more here.
Keywords: monoclonal antibody; therapies management; management sars; cov infection ... See more keywords
Antibody therapies for multiple myeloma
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DOI: 10.1080/14712598.2020.1717464
Abstract: ABSTRACT Introduction: Multiple myeloma (MM) is characterized by the uncontrollable proliferation of plasma cells and the excessive production of a specific type of immunoglobulin. Immune system is deregulated in MM and, thus, immunotherapy is a… read more here.
Keywords: myeloma; antibody therapies; multiple myeloma; therapies multiple ... See more keywords
Editorial: Updates on convalescent plasma and monoclonal antibody therapies for infectious disease in patients with primary immunodeficiency
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1010072
Abstract: COPYRIGHT © 2022 Condino-Neto and Gennery. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the… read more here.
Keywords: monoclonal antibody; updates convalescent; editorial updates; antibody therapies ... See more keywords
Uses and Challenges of Antiviral Polyclonal and Monoclonal Antibody Therapies
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DOI: 10.3390/pharmaceutics15051538
Abstract: Viral diseases represent a major public health concerns and ever-present risks for developing into future pandemics. Antiviral antibody therapeutics, either alone or in combination with other therapies, emerged as valuable preventative and treatment options, including… read more here.
Keywords: antiviral polyclonal; uses challenges; challenges antiviral; polyclonal monoclonal ... See more keywords