Factors Associated With Patients Not Receiving Oral Anticancer Drugs
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.36380
Abstract: Key Points Question How many patients with cancer do not receive oral anticancer drug prescriptions, and what are the factors associated with this failure to receive these drugs? Findings A cohort study of 1024 patients… read more here.
Keywords: anticancer drugs; anticancer drug; factors associated; anticancer ... See more keywords
Targeting senescence as an anticancer therapy
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13312
Abstract: Cellular senescence is a stress response elicited by different molecular insults. Senescence results in cell cycle exit and is characterised by multiple phenotypic changes such as the production of a bioactive secretome. Senescent cells accumulate… read more here.
Keywords: one two; senescence; senescent cells; anticancer ... See more keywords
Nanocomplexes of Biodegradable Anticancer Macromolecules: Prolonged Plasma Half-life, Reduced Toxicity, and Increased Tumor Targeting.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202201560
Abstract: Anticancer drug resistance is a large contributing factor to the global mortality rate of cancer patients. Anticancer macromolecules such as polymers were recently reported to overcome this issue. Anticancer macromolecules have unselective toxicity because they… read more here.
Keywords: toxicity; half; anticancer macromolecules; anticancer ... See more keywords
A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202501847
Abstract: As FDA‐approved platinum (Pt) anticancer drugs (e.g. cisplatin, oxaliplatin and carboplatin) grapple with clinical challenges including chemoresistance and systemic side‐effects, Pt(IV) prodrugs have emerged as potent alternative chemotherapies. In this work, a novel bimetallic dual‐action… read more here.
Keywords: anticancer; dual action; action prodrug; prodrug displays ... See more keywords
Antineoplastic Drug-Free Anticancer Strategy Enabled by Host-Defense-Peptides-Mimicking Synthetic Polypeptides.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202001108
Abstract: An antineoplastic drug-free anticancer strategy enabled by host defense peptides (HDPs)-mimicking synthetic polypeptides is reported. The polypeptide exhibits a broad spectrum of anticancer activity in 12 cancer cell lines, including drug-resistant and highly metastatic tumor… read more here.
Keywords: anticancer strategy; antineoplastic drug; drug; free anticancer ... See more keywords
Blocking Spatiotemporal Crosstalk between Subcellular Organelles for Enhancing Anticancer Therapy with Nanointercepters
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202211597
Abstract: The spatiotemporal characterization of signaling crosstalk between subcellular organelles is crucial for the therapeutic effect of malignant tumors. Blocking interactive crosstalk in this fashion is significant but challenging. Herein, a communication interception strategy is reported,… read more here.
Keywords: subcellular organelles; spatiotemporal crosstalk; anticancer; therapy ... See more keywords
Honokiol‐Magnolol‐Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti‐PD‐1 Immunotherapy in Colorectal Cancer by Triggering GSDME‐Dependent Pyroptosis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202417022
Abstract: Significant progress is made in the treatment of metastatic colorectal cancer (mCRC) patients, however, therapeutic options remain limited for patients with mCRC. In recent years, traditional Chinese medicine (TCM) has gained significant attention. Among these,… read more here.
Keywords: colorectal cancer; anticancer; efficacy; anti immunotherapy ... See more keywords
Exploring Bacteria‐Based Cancer Immunotherapy: Comment on “Discovery of Intratumoral Oncolytic Bacteria Toward Targeted Anticancer Theranostics”
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202506869
Abstract: A recent study by Goto et al. [1] piqued our interest in oncolytic bacteria as anticancer theranostics. In this report, the authors describe a unique tumor-resident bacteria ( Proteus mirabilis , PM), combined with natural… read more here.
Keywords: oncolytic bacteria; anticancer; based cancer; anticancer theranostics ... See more keywords
Synthesis and Characterization of a New Neodymium Complex: DFT Insights and Potential Anticancer Applications
Sign Up to like & getrecommendations! Published in 2025 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.70067
Abstract: A new complex of type [Nd (HL) (NO3)2] has been synthesized with a Schiff base ligand H2L derived from 2‐hydroxy‐3‐methoxybenzaldehyde and L‐histidine. The structure of the synthesized complex was established using elemental analysis, molar conductivities,… read more here.
Keywords: iii; anticancer; dft; ligand ... See more keywords
Modulating the Anticancer Activity of Square‐Planar Platinum (II) Complex by Its Chelated Diphosphine
Sign Up to like & getrecommendations! Published in 2024 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.7803
Abstract: This work reports the preparations and anticancer activities of a set of platinum (II) complexes. Two types of bidentate ligands, azadiphosphine (PNP) and diphosphine (PP), were applied to afford different kinds of platinum centers, the… read more here.
Keywords: diphosphine; anticancer; anticancer activities; modulating anticancer ... See more keywords
Selective Metal‐Coordinated Nanodrugs Based on Thiazine Moiety for Anticancer Therapeutics: Spectroscopic, Theoretical, and Molecular Docking Studies
Sign Up to like & getrecommendations! Published in 2024 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.7840
Abstract: The current study involved production, comprehensive structural analysis, and physicochemical characterizing of two distinctive complexes namely, Cu(TBH) and Zn(TBH); TBH donor ligand: N′‐(1‐(3,6‐dihydro‐4‐hydroxy‐2,6‐dioxo‐2H‐1,3‐thiazin‐5‐yl)ethylidene)‐2‐hydroxybenzohydrazide) using a wide range of analytical methods, including elemental analysis, UV–Vis, FT‐IR,… read more here.
Keywords: docking studies; anticancer; cell line; geometry ... See more keywords