Early Steps of the Biosynthesis of the Anticancer Antibiotic Pleurotin
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DOI: 10.1021/acschembio.4c00599
Abstract: Pleurotin is a meroterpenoid specialised metabolite made by the fungus Hohenbuehelia grisea, and it is a lead anticancer molecule due to its irreversible inhibition of the thioredoxin-thioredoxin reductase system. Total synthesis of pleurotin has previously… read more here.
Keywords: early steps; anticancer antibiotic; biosynthesis anticancer; steps biosynthesis ... See more keywords