Synthesis and biological screening of a novel enaminone-grafted trithiocarbonate: a potential anticancer and antimicrobial agent
Sign Up to like & getrecommendations! Published in 2020 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-020-02535-2
Abstract: A need exists to develop safe and efficacious medications to treat major diseases such as cancer and infectious diseases. In response to this need, we synthesized a novel enaminone, which structurally belongs to the trithiocarbonate… read more here.
Keywords: biological screening; screening novel; novel enaminone; synthesis biological ... See more keywords
First evidence of anticancer and antimicrobial activity in Mediterranean mesopelagic species
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-61515-z
Abstract: Mesopelagic organisms form huge biomass aggregations, supporting important pelagic trophic webs and several top predators. Although some studies on the occurrence, biology and ecology of these organisms are available, to date there are no investigations… read more here.
Keywords: mesopelagic species; anticancer antimicrobial; cell line; activity ... See more keywords
Sn(IV)-porphyrinoids for photodynamic anticancer and antimicrobial chemotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d3dt00603d
Abstract: Photodynamic therapy (PDT) is a mode of treatment for different types of cancers, which involves a nontoxic photosensitizer (PS), a light source to activate the PS, and ground-state molecular oxygen (3O2). Light activation of the… read more here.
Keywords: antimicrobial chemotherapy; porphyrinoids photodynamic; oxygen; photodynamic anticancer ... See more keywords
Synthesis, anticancer and antimicrobial evaluation of new pyridyl and thiazolyl clubbed hydrazone scaffolds
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1692870
Abstract: Abstract A series of new hydrazones bearing pyridyl and thiazolyl scaffolds have been synthesized and evaluated for their in vitro anticancer and antimicrobial activities. The anticancer activity was evaluated against the A549 lung cancer cell… read more here.
Keywords: synthesis anticancer; pyridyl thiazolyl; anticancer antimicrobial; hydrazone derivatives ... See more keywords
Anticancer and antimicrobial potential of enterocin 12a from Enterococcus faecium
Sign Up to like & getrecommendations! Published in 2021 at "BMC Microbiology"
DOI: 10.1186/s12866-021-02086-5
Abstract: Background Increase in the number of infections caused by Gram-negative bacteria in neutropenic cancer patients has prompted the search for novel therapeutic agents having dual anticancer and antimicrobial properties. Bacteriocins are cationic proteins of prokaryotic… read more here.
Keywords: enterococcus faecium; anticancer antimicrobial; enterocin 12a;
Anticancer, Antimicrobial and Antioxidant Activities of the Essential Oils of Some Aromatic Medicinal Plants (Pulicaria inuloides-Asteraceae)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Food and Nutrition Research"
DOI: 10.12691/jfnr-5-7-6
Abstract: Purpose: To determine the anticancer, antimicrobial and antioxidant activities of Pulicaria inuloides essential oil (PiEO). Methods: 3-(4, 5-dimethylthiazol- 2-yl)-2, 5-diphenyltetrazolium bromide (MTT) was used to assess cytotoxic activity. Steam distillation of the aerial parts of… read more here.
Keywords: antimicrobial antioxidant; antioxidant activities; pulicaria inuloides; essential oils ... See more keywords
Synthesis of novel sulphamethoxazole derivatives and exploration of their anticancer and antimicrobial properties
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0283289
Abstract: A series of new derivatives based on sulfamethoxazole were designed and synthesized in this study. The structures of the new compounds were confirmed based on a comprehensive characterization of spectral data by applied IR and… read more here.
Keywords: cell; novel sulphamethoxazole; antimicrobial properties; synthesis novel ... See more keywords
Antioxidant, Anticancer, Antimicrobial, and Antibiofilm Properties of the Culinary-Medicinal Fairy Ring Mushroom, Marasmius oreades (Agaricomycetes).
Sign Up to like & getrecommendations! Published in 2019 at "International journal of medicinal mushrooms"
DOI: 10.1615/intjmedmushrooms.2019030874
Abstract: This study is based on the phenolic composition and the antioxidant, anticancer, antimicrobial, and antibiofilm activities of the edible mushroom Marasmius oreades from Turkey. The phenolic composition of an M. oreades ethanol extract was measured… read more here.
Keywords: ethanol extract; anticancer antimicrobial; antioxidant anticancer; activity ... See more keywords
Novel Organoselenium Redox Modulators with Potential Anticancer, Antimicrobial, and Antioxidant Activities
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11071231
Abstract: Novel organic selenides were developed in good yields (up to 91%), and their chemical entities were confirmed by IR, MS, and 1H- and 13C-NMR spectroscopy. Their anticancer and antimicrobial properties were estimated against different human… read more here.
Keywords: novel organoselenium; organoselenium redox; antioxidant activities; redox modulators ... See more keywords
Anticancer, Antimicrobial, and Antioxidant Activities of Organodiselenide-Tethered Methyl Anthranilates
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12121765
Abstract: Novel methyl anthranilate-based organodiselenide hybrids were synthesized, and their chemical structures were confirmed by state-of-the-art spectroscopic techniques. Their antimicrobial properties were assessed against Staphylococcus aureus, Escherichia coli, and Candida albicans microbial strains. Moreover, the antitumor… read more here.
Keywords: organodiselenide tethered; activities organodiselenide; antioxidant activities; antimicrobial antioxidant ... See more keywords
Synthesis and Biological Evaluation of Novel Aminochalcones as Potential Anticancer and Antimicrobial Agents
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24224129
Abstract: A series of 18 aminochalcone derivatives were obtained in yields of 21.5–88.6% by applying the classical Claisen-Schmidt reaction. Compounds 4–9, 14 and 16–18 with 4-ethyl, 4-carboxy-, 4-benzyloxy- and 4-benzyloxy-3-methoxy groups were novel, not previously described… read more here.
Keywords: biological evaluation; aminochalcone; coli atcc10536; synthesis biological ... See more keywords