De Novo Biosynthesis of the Anticancer Compound Euphol in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2021 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00257
Abstract: Euphol is a euphane-type tetracyclic triterpene which is primarily found in the Euphorbia genus. Euphol has been renowned because of its great potential as a promising anticancer drug. Surprisingly, despite its diverse antitumor effects, the… read more here.
Keywords: euphol; saccharomyces cerevisiae; biosynthesis anticancer; novo biosynthesis ... See more keywords
PaccMann: a web service for interpretable anticancer compound sensitivity prediction
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa327
Abstract: Abstract The identification of new targeted and personalized therapies for cancer requires the fast and accurate assessment of the drug efficacy of potential compounds against a particular biomolecular sample. It has been suggested that the… read more here.
Keywords: anticancer compound; drug; sensitivity; compound ... See more keywords
Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27248819
Abstract: Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties, such as antioxidant, antidiabetic, anti-inflammatory, and antitumor activities. In this review… read more here.
Keywords: phloretin potent; chemistry; anticancer; anticancer compound ... See more keywords