Comparative in vitro investigation of anticancer copper chelating agents
Sign Up to like & getrecommendations! Published in 2018 at "Microchemical Journal"
DOI: 10.1016/j.microc.2016.12.007
Abstract: Abstract Evaluation of in vitro cytotoxicity of several Cu chelating agents - 2,2′-biquinoline, 8-hydroxyquinoline (oxine), ammonium pyrrolidinedithiocarbamate (APDTC), di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone (Dp44mT), dithizone and neocuproine – on HT-29 human colon adenocarcinoma as well as long term in… read more here.
Keywords: vitro investigation; long term; chelating agents; investigation anticancer ... See more keywords
Liposomal formulations of anticancer copper(II) thiosemicarbazone complexes.
Sign Up to like & getrecommendations! Published in 2021 at "Dalton transactions"
DOI: 10.1039/d1dt02763h
Abstract: α-N-Heterocyclic thiosemicarbazones such as triapine and COTI-2 are currently investigated as anticancer therapeutics in clinical trials. However, triapine was widely inactive against solid tumor types. A likely explanation is the short plasma half-life time and… read more here.
Keywords: anticancer copper; copper; formulations anticancer; drug ... See more keywords