Anticancer and Cytotoxic Activities of [Cu(C6H16N2O2)2][Ni(CN)4] and [Cu(C6H16N2O2)Pd(CN)4] Cyanidometallate Compounds on HT29, HeLa, C6 and Vero Cell Lines.
Sign Up to like & getrecommendations! Published in 2017 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520617666170103102417
Abstract: BACKGROUND In cancer, apoptosis relevant proteins-such as CaM kinase, Bcl-2 or P53, topoisomerase I, cell migration feature and DNA/BSA-macromolecules represent significant targets for current chemotherapeutics. OBJECTIVE We recently reported two coordination compounds-[Cu(C6H16N2O2)2][Ni(CN)4] (1) and [Cu(C6H16… read more here.
Keywords: anticancer cytotoxic; cytotoxic activities; vero; spectroscopy ... See more keywords
Anticancer Cytotoxic Activity of Bispidine Derivatives Associated with the Increasing Catabolism of Polyamines
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27123872
Abstract: Polyamine (PA) catabolism is often reduced in cancer cells. The activation of this metabolic pathway produces cytotoxic substances that might cause apoptosis in cancer cells. Chemical compounds able to restore the level of PA catabolism… read more here.
Keywords: cancer; bispidine derivatives; anticancer cytotoxic; catabolism ... See more keywords
Evaluation of Anticancer and Cytotoxic Effects of Genistein on PC3 Prostate Cell Line under Three-Dimensional Culture Medium
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Biomedical Journal"
DOI: 10.52547/ibj.3711
Abstract: Background: Prostate cancer is a major cause of disease and mortality among men. GNT is an isoflavone found naturally in legumes. Isoflavones, a subset of phytoestrogens, are structurally similar to mammalian estrogens. This study aimed… read more here.
Keywords: culture; cytotoxic effects; anticancer cytotoxic; pc3 cells ... See more keywords