Factors Associated With Patients Not Receiving Oral Anticancer Drugs
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.36380
Abstract: Key Points Question How many patients with cancer do not receive oral anticancer drug prescriptions, and what are the factors associated with this failure to receive these drugs? Findings A cohort study of 1024 patients… read more here.
Keywords: anticancer drugs; anticancer drug; factors associated; anticancer ... See more keywords
Vascularized lung cancer model for evaluating the promoted transport of anticancer drugs and immune cells in an engineered tumor microenvironment.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202102581
Abstract: The tumor microenvironment (TME) is the environment around the tumor, including blood vessels, immune cells, fibroblasts, signaling molecules, and the extracellular matrix (ECM). Owing to its component interactions, the TME influences tumor growth and drug… read more here.
Keywords: tumor; cancer; immune cells; microenvironment ... See more keywords
Is ASCT2 a Suitable Vector for the Selective Delivery of Anticancer Drugs? Modification of Glutamine at Either the Carboxylate or the Side Chain Hinders Binding and Transport
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202400759
Abstract: The Alanine, Serine, and Cysteine Transporter 2 (ASCT2) transports glutamine into cells and is upregulated in many cancers. Attachment to glutamine to enable ASCT2 to transport anticancer agents into cells has been proposed, but the… read more here.
Keywords: transport; anticancer; modification glutamine; glutamine ... See more keywords
Environmental Hazard of Anticancer Drugs: State of the Art and Future Perspective for Marine Organisms
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5397
Abstract: Pharmaceutical compounds represent a class of emerging contaminants present in the environment. Their intense (and increasing) use in human and veterinary medicine leads to their discharge, mainly via human excretion, into wastewater treatment plants where… read more here.
Keywords: anticancer drugs; hazard anticancer; drugs state; environmental hazard ... See more keywords
Structure‐property modeling of pharmacokinetic characteristics of anticancer drugs via topological indices, multigraph modeling and multi‐criteria decision making
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Quantum Chemistry"
DOI: 10.1002/qua.27428
Abstract: This study presents an in‐depth inquiry into estimating ADME properties for promising anticancer drugs, particularly amino acid‐based alkylating agents, through ev‐ve degree topological indices and QSPR analysis. The aim of the study is to compare… read more here.
Keywords: structure; decision making; topological indices; anticancer drugs ... See more keywords
Theoretical study of boron nitride nanotubes as drug delivery vehicles of some anticancer drugs
Sign Up to like & getrecommendations! Published in 2018 at "Theoretical Chemistry Accounts"
DOI: 10.1007/s00214-018-2284-2
Abstract: Due to the toxicity and resistance of the anticancer drugs, various methods were employed to improve their efficacy in cancer treatment. Studies illustrated that these drugs could bind to the boron nitride nanotubes (BNNTs) surface… read more here.
Keywords: drug delivery; boron nitride; drug; anticancer drugs ... See more keywords
Safety assessment of anticancer drugs in association with radiotherapy in metastatic malignant melanoma: a real-life report
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03806-5
Abstract: PurposeTo assess the safety of the association of radiotherapy (RT) and systemic treatments for patients with metastatic malignant melanoma (mMM).MethodsA retrospective analysis included consecutive patients treated with palliative RT, and at least one line of… read more here.
Keywords: metastatic malignant; safety; association; anticancer drugs ... See more keywords
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-024-04640-0
Abstract: The number of patients with bariatric surgery who receive oral anticancer drugs is rising. Bariatric surgery may affect the absorption of oral anticancer drugs. Strikingly, no specific drug dosing recommendations are available. We aim to… read more here.
Keywords: anticancer drugs; risk; oral anticancer; bariatric surgery ... See more keywords
A new original approach to the design of anticancer drugs based on energy-rich quadricyclanes
Sign Up to like & getrecommendations! Published in 2019 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-019-2516-1
Abstract: Quadricyclane derivatives are shown for the first time to be promising for application as anticancer drugs. The efficiency of such cage compounds is mainly due to thermal action on cancer cells resulting from a C—C… read more here.
Keywords: new original; original approach; anticancer drugs; approach design ... See more keywords
Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-9525-0
Abstract: The distributions of 31 pharmaceuticals grouped into nine therapeutic classes, including six anticancer drugs, were investigated in the waters and sediments of an urban river in Japan. The coefficients of sorption (logKd) to the river… read more here.
Keywords: sediments urban; river; anticancer drugs; six anticancer ... See more keywords
Photoactivated platinum-based anticancer drugs
Sign Up to like & getrecommendations! Published in 2018 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2018.08.009
Abstract: Abstract Following the serendipitous discovery of the anticancer drug, cisplatin, numerous platinum(II) complexes have been synthesized and some of them, such as carboplatin, oxaliplatin, nedaplatin, heptaplatin and lobaplatin, have been clinically approved either locally or… read more here.
Keywords: platinum; platinum based; based anticancer; anticancer drugs ... See more keywords