Sign Up to like & get
recommendations!
1
Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113241
Abstract: The synthesis of a new set of triazole bisphosphonates 8a-d and 9a-d presenting an alkyl or phenyl substituent at the C-4 or C-5 position of the triazole ring is described. These compounds have been evaluated…
read more here.
Keywords:
anticancer evaluation;
new triazole;
biosynthesis;
evaluation new ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
0
Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2019.04.018
Abstract: Abstract In this study, the synthesis and characterization of new paramagnetic ruthenium(III) complexes: cis-[RuCl2(urdpa)] (1) {Hurdpa = 6-((bis(pyridin-2-ylmethyl)amino)methyl)uracil} and fac-[RuCl3(chrdpa)] (2) {chrdpa = 4-((bis(pyridin-2-ylmethyl)amino)methyl)-7-methoxycoumarin} are reported. These metal complexes have been comprehensively characterized by an array of physicochemical techniques…
read more here.
Keywords:
ruthenium iii;
ruthenium;
evaluation ruthenium;
iii complexes ... See more keywords
Photo from archive.org
Sign Up to like & get
recommendations!
0
Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128486
Abstract: Abstract Six phosphanegold(I)-dithiocarbamate complexes (1–6) of general formula [Au(L)(S2CNR2)] (where L = 2-(di-isopropylphosphanyl)-1-aminoethane (AEP) and 3-(di-isopropylphosphanyl)-1-aminopropane (APP), and R = methyl, ethyl, benzyl) were prepared by the reactions of equimolar amounts of (CH3)2S–AuCl, phosphanes and dithiocarbamates (S2CNR2) in dichloromethane.…
read more here.
Keywords:
anticancer evaluation;
evaluation phosphanegold;
dft optimization;
characterization dft ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2021 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2020.1870507
Abstract: N'-(2-((4-(Benzo[d][1, 3]dioxol-5-yl)-3-cyano-6-(naphthalen-2-yl)-pyridin-2-yl)oxy)- acetyl)benzohydrazide (6) and hydrazide derivatives (7–10) were synthesized via reaction of 3-cyano-pyridinaceto...
read more here.
Keywords:
anticancer evaluation;
pyridine carbonitrile;
docking anticancer;
synthesis docking ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010854
Abstract: New N-alkylindole-substituted 2-(pyrid-3-yl)-acrylonitriles with putative kinase inhibitory activity and their (p-cymene)Ru(II) piano-stool complexes were prepared and tested for their antiproliferative efficacy in various cancer models. Some of the indole-based derivatives inhibited tumor cell proliferation at…
read more here.
Keywords:
evaluation new;
synthesis anticancer;
new indole;
anticancer evaluation ... See more keywords
Sign Up to like & get
recommendations!
2
Published in 2023 at "Molecules"
DOI: 10.3390/molecules28020626
Abstract: Hybrid compounds of flavones, namely chrysin and kaempferol, and substituted 1,2,3-triazole derivatives, were synthesized by click reaction of the intermediate O-propargyl derivatives. 4-Fluoro- and 4-nitrobenzyl-1,2,3-triazole-containing hybrid molecules were prepared. The mono- and bis-coupled hybrids were…
read more here.
Keywords:
vitro anticancer;
synthesis vitro;
flavone triazole;
triazole hybrids ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
1
Published in 2023 at "Molecules"
DOI: 10.3390/molecules28114457
Abstract: The role of hypoxic tumour cells in resistance to radiotherapy, and in suppression of immune response, continues to endorse tumour hypoxia as a bona fide, yet largely untapped, drug target. Radiotherapy innovations such as stereotactic…
read more here.
Keywords:
design synthesis;
evaluation nitroimidazole;
synthesis anticancer;
radiotherapy ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
0
Published in 2021 at "Research Journal of Pharmacy and Technology"
DOI: 10.52711/0974-360x.2021.00382
Abstract: In the present study, a series of novel substituted pyrazole chalcones and pyrazole oximes (CF 1-15) were synthesized and characterized. Logp values were determined to assess their hydrophobicity. MTT (methyl tetrazolium) assay was performed on…
read more here.
Keywords:
synthesis characterization;
characterization anticancer;
evaluation novel;
novel ... See more keywords