Aminonaphthalimide hybrids of mitoxantrone and amonafide as anticancer and fluorescent cellular imaging agents.
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DOI: 10.1016/j.bioorg.2019.103287
Abstract: Novel water-soluble 4-aminonaphthalimides were synthesised and their cellular fluorescent imaging, cytotoxicity and ability to induced apoptosis evaluated. The lead compound 1 was designed from the cross-fertilisation of the basic hydrophilic amino pharmacophore of mitoxantrone, and… read more here.
Keywords: cellular imaging; anticancer fluorescent; microscopy; fluorescent ... See more keywords