The relationship of nutritional status with anticancer immunity and its prognostic value for head and neck cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular carcinogenesis"
DOI: 10.1002/mc.23584
Abstract: Malnutrition has been reported to be associated with reduced survival and deficient anticancer immunity, and undernourishment is a frequent comorbidity in head and neck cancer (HNC) patients. In this study, we evaluated the relationship between… read more here.
Keywords: nutritional status; hnc patients; hnc; tumor ... See more keywords
Hollow ZnO Nanospheres Enhance Anticancer Immunity by Promoting CD4+ and CD8+ T Cell Populations In Vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Small"
DOI: 10.1002/smll.201701816
Abstract: Appropriate adjuvant aiding in generating robust anticancer immunity is crucial for cancer immunotherapy. Herein, hollow ZnO (HZnO) nanospheres are synthesized by a facile method using carbon nanospheres as the template. The HZnO nanospheres significantly promote… read more here.
Keywords: hollow zno; anticancer immunity; hzno; model ... See more keywords
Paradoxical roles of mutational load as a determinant of anticancer immunity
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/s41571-019-0282-5
Abstract: Immune-checkpoint inhibitors (ICIs) have reshaped oncology practice, but continued research is required to understand why only a minority of patients have durable responses and to better identify this subgroup. A high tumour mutational burden (TMB)… read more here.
Keywords: cell; anticancer immunity; effect; tmb ... See more keywords
Tumor lysis with LTX-401 creates anticancer immunity
Sign Up to like & getrecommendations! Published in 2019 at "OncoImmunology"
DOI: 10.1080/2162402x.2019.1594555
Abstract: ABSTRACT Local immunotherapies such as the intratumoral injection of oncolytic compounds aim at reinstating and enhancing systemic anticancer immune responses. LTX-315 is a first-in-class, clinically evaluated oncolytic peptide-based local immunotherapy that meets these criteria. Here,… read more here.
Keywords: creates anticancer; ltx 401; lysis ltx; anticancer immunity ... See more keywords
Interleukin-2 signals converge in a lymphoid–dendritic cell pathway that promotes anticancer immunity
Sign Up to like & getrecommendations! Published in 2020 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aba5464
Abstract: IL-2 immunotherapy expands tumor-infiltrating DCs through a lymphoid pathway, favoring the conversion of poorly immunogenic into immunogenic tumors. Hidden virtues of interleukin-2 Interleukin-2 (IL-2) is an immunostimulatory cytokine that is being tested as an anticancer… read more here.
Keywords: dcs; immunity; dendritic cell; anticancer immunity ... See more keywords
Microbiota Manipulated to Enhance Anticancer Immunity.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-nd2019-004
Abstract: Oncologists are testing fecal transplants and other microbiome-based products in combination with checkpoint inhibitors in an effort to increase and enhance responses. However, questions remain about how the microbes affect host immunity and which preparations… read more here.
Keywords: immunity; manipulated enhance; anticancer immunity; enhance anticancer ... See more keywords
The Impact of Tregs on the Anticancer Immunity and the Efficacy of Immune Checkpoint Inhibitor Therapies
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.625783
Abstract: Although cancers arise from genetic mutations enabling cells to proliferate uncontrollably, they cannot thrive without failure of the anticancer immunity due in a large part to the tumor environment's influence on effector and regulatory T… read more here.
Keywords: immune checkpoint; immunity; efficacy; anticancer immunity ... See more keywords
Lactic Acid and an Acidic Tumor Microenvironment suppress Anticancer Immunity
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21218363
Abstract: Immune evasion and altered metabolism, where glucose utilization is diverted to increased lactic acid production, are two fundamental hallmarks of cancer. Although lactic acid has long been considered a waste product of this alteration, it… read more here.
Keywords: acid; tumor microenvironment; anticancer immunity; lactic acid ... See more keywords