ACP_MS: prediction of anticancer peptides based on feature extraction
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac462
Abstract: Anticancer peptides (ACPs) are bioactive peptides with antitumor activity and have become the most promising drugs in the treatment of cancer. Therefore, the accurate prediction of ACPs is of great significance to the research of… read more here.
Keywords: anticancer peptide; anticancer peptides; prediction; peptide sequences ... See more keywords
Biophysical Characterization of LTX-315 Anticancer Peptide Interactions with Model Membrane Platforms: Effect of Membrane Surface Charge
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810558
Abstract: LTX-315 is a clinical-stage, anticancer peptide therapeutic that disrupts cancer cell membranes. Existing mechanistic knowledge about LTX-315 has been obtained from cell-based biological assays, and there is an outstanding need to directly characterize the corresponding… read more here.
Keywords: ltx 315; spectroscopy; anticancer peptide; membrane ... See more keywords
The Structures of Heterogeneous Membranes and Their Interactions with an Anticancer Peptide: A Molecular Dynamics Study
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12101473
Abstract: We conduct molecular dynamics simulations of model heterogeneous membranes and their interactions with a 24-amino acid peptide—NAF-144–67. NAF-144–67 is an anticancer peptide that selectively permeates and kills malignant cells; it does not permeate normal cells.… read more here.
Keywords: heterogeneous membranes; molecular dynamics; anticancer peptide; interactions anticancer ... See more keywords