Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113652
Abstract: Indirubin is the crucial ingredient of Danggui Longhui Wan and Qing-Dai, traditional Chinese medicine herbal formulas used for the therapy of chronic myelocytic leukemia in China for hundreds of years. Although the monomeric indirubin has… read more here.
Keywords: structural modification; modification structure; chemistry; potential indirubins ... See more keywords
Antioxidant and anticancer potential of bioactive compounds following UV-C light-induced plant cambium meristematic cell cultures
Sign Up to like & getrecommendations! Published in 2017 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2017.09.024
Abstract: Abstract Catharanthus roseus (L.) G. Don is a well-known medicinal plant as a potent anticancer agent that produces rich of secondary metabolites, such as phytochemicals, terpenoid indole alkaloids (TIAs) including catharanthine, vinblastine, vincristine, vindoline. In… read more here.
Keywords: cambium meristematic; plant; antioxidant anticancer; bioactive compounds ... See more keywords
Diastereoselective synthesis and anticancer potential of a small library of cage-like heterocyclic hybrids
Sign Up to like & getrecommendations! Published in 2021 at "Journal of King Saud University - Science"
DOI: 10.1016/j.jksus.2020.101238
Abstract: Abstract With an aim to construct novel anticancer drugs, a series of polycyclic heterocycles comprising diverse structural sub-units based on molecular hybridization strategy have been designed and synthesized through a three-component [3+2]-cycloaddition/annulation strategy. Anticancer evaluation… read more here.
Keywords: diastereoselective synthesis; synthesis anticancer; potential small; anticancer ... See more keywords
Nigerian antimalarial plants and their anticancer potential: A review.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of integrative medicine"
DOI: 10.1016/j.joim.2020.01.001
Abstract: Cancer is a leading cause of death globally, while malaria is the leading cause of death from parasitic diseases in Nigeria. Historically, plant remedies have been used to manage both cancer and malaria. Interestingly, the… read more here.
Keywords: antimalarial plants; nigerian antimalarial; cancer; anticancer ... See more keywords
A mechanistic review of the anticancer potential of hesperidin, a natural flavonoid from citrus fruits.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition research"
DOI: 10.1016/j.nutres.2021.05.011
Abstract: Hesperidin, a phytoactive compound, is an abundant and economical dietary bioflavonoid possessing numerous biological and medicinal benefits. Several studies have strongly proven the significant chemotherapeutic potential of hesperidin. Therefore, this review aims to bring together… read more here.
Keywords: mechanistic review; review anticancer; potential hesperidin; hesperidin ... See more keywords
A study of deregulated MMR pathways and anticancer potential of curcuma derivatives using computational approach
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89282-5
Abstract: Plant derived products have steadily gained momentum in treatment of cancer over the past decades. Curcuma and its derivatives, in particular, have diverse medicinal properties including anticancer potential with proven safety as supported by numerous… read more here.
Keywords: mmr pathways; study; deregulated mmr; curcuma derivatives ... See more keywords
Elucidation of the anticancer potential and tubulin isotype-specific interactions of β-sitosterol
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2016.1271749
Abstract: Beta-sitosterol (β-SITO), a phytosterol present in many edible vegetables, has been reported to possess antineoplastic properties and cancer treatment potential. We have shown previously that it binds at a unique site (the ‘SITO-site’) compared to… read more here.
Keywords: isotype; elucidation anticancer; sito; potential tubulin ... See more keywords
Natural products based crown ethers: synthesis and their anticancer potential.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2021.1918118
Abstract: Natural products based novel crown ethers have been prepared by employing biologically active natural structures including tetrahydroisoquinoline, chrysin and biochanin-A as the side arms. The resulting crown scaffolds were evaluated for their anticancer potential against… read more here.
Keywords: natural products; lung carcinoma; products based; anticancer potential ... See more keywords
The chemopreventive and anticancer potential against colorectal cancer of polyphenol-rich fruit extracts
Sign Up to like & getrecommendations! Published in 2018 at "Food Reviews International"
DOI: 10.1080/87559129.2017.1307388
Abstract: ABSTRACT The consumption of vegetables and fruits, particularly apples, pomegranates, grapes, and berries, is associated with a decreased risk of developing cancer, especially colorectal cancer (CRC). This may be attributable to the presence of phytochemical… read more here.
Keywords: colorectal cancer; chemopreventive anticancer; polyphenol rich; cancer ... See more keywords
Characterization and Anticancer Potential of Silver Nanoparticles Biosynthesized from Olea chrysophylla and Lavandula dentata Leaf Extracts on HCT116 Colon Cancer Cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Nanomaterials"
DOI: 10.1155/2019/7361695
Abstract: Cancer was ranked as the second leading cause of death, and colon cancer has been reported as the third most frequent cancer worldwide. Chemotherapeutic drugs act on normal and cancerous cells similarly; therefore, they have… read more here.
Keywords: cancer; anticancer potential; silver nanoparticles; lav agnps ... See more keywords
Anticancer Potential of Moringa oleifera on BRCA-1 Gene: Systems Biology
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics and Biology Insights"
DOI: 10.1177/11779322211010703
Abstract: Breast cancer has consistently been a global challenge that is prevalent among women. There is a continuous increase in the high number of women mortality rates because of breast cancer and affecti... read more here.
Keywords: brca gene; potential moringa; oleifera brca; moringa oleifera ... See more keywords