Stability, Reduction, and Cytotoxicity of Platinum(IV) Anticancer Prodrugs Bearing Carbamate Axial Ligands: Comparison with Their Carboxylate Analogues.
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DOI: 10.1021/acs.inorgchem.0c01541
Abstract: Platinum(IV) complexes containing carboxylate and carbamate ligands at the axial position have been reported previously. A better understanding of the similarity and difference between the two types of ligands will provide us with new insights… read more here.
Keywords: anticancer prodrugs; carboxylate; stability; carbamate axial ... See more keywords
Ligand Evolution in the Photoactivatable Platinum(IV) Anticancer Prodrugs
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DOI: 10.3389/fchem.2022.876410
Abstract: Photoactivatable Pt(IV) anticancer prodrugs with the structure of [PtIV(N1)(N2)(L1)(L2)(A1)(A2)], where N1 and N2 are non-leaving nitrogen donor ligands, L1 and L2 are leaving ligands, and A1 and A2 are axial ligands, have attracted increasing attention… read more here.
Keywords: evolution photoactivatable; photoactivatable platinum; anticancer prodrugs; anticancer ... See more keywords