Potentiometric Determination of Acid Dissociation Constants (pK a) for an Anticancer Pyrrole-Imidazole Polyamide.
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DOI: 10.1021/acsmedchemlett.2c00348
Abstract: To optimize the pharmacological properties of an anticancer pyrrole-imidazole (Py-Im) polyamide (PIP-1), we characterized the acid dissociation constants of PIP-1, three other structurally related hairpin-shaped polyamides, and a cyclic polyamide bearing the same core sequence… read more here.
Keywords: dissociation constants; pyrrole imidazole; dissociation; acid dissociation ... See more keywords