Anticancer therapeutic potential of multimodal targeting agent- “phosphorylated galactosylated chitosan coated magnetic nanoparticles” against N-nitrosodiethylamine-induced hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-024-01655-1
Abstract: Superparamagnetic iron oxide nanoparticles (SPIONs) are extensively used as carriers in targeted drug delivery and has several advantages in the field of magnetic hyperthermia, chemodynamic therapy and magnet assisted radionuclide therapy. The characteristics of SPIONs… read more here.
Keywords: galactosylated chitosan; anticancer therapeutic; phosphorylated galactosylated; agent ... See more keywords
Arabinogalactan-Functionalized Gold Nanoparticles Demonstrated Remarkable Anticancer Therapeutic Effect against Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.5c00598
Abstract: The treatment and prognosis of cancer remain highly challenging due to its complex and multifaceted nature. In the paradigm of nanomedicine, nanotechnology has gained huge attention in cancer therapeutics. The unique physicochemical properties offered by… read more here.
Keywords: cancer; anticancer therapeutic; therapeutic effect; hepatocellular carcinoma ... See more keywords
(-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery"
DOI: 10.1080/10717544.2019.1672830
Abstract: Abstract Realgar and (-)-Epigallocatechin-3-gallate (EGCG) are natural medicines that inhibit cancer cell growth, resulting in inhibition of formation and development of tumors. The anticancer effects of realgar and EGCG were greatly improved following formulation as… read more here.
Keywords: egcg rnps; epigallocatechin gallate; egcg; realgar ... See more keywords
FNC: An Advanced Anticancer Therapeutic or Just an Underdog?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.820647
Abstract: Azvudine (FNC) is a novel cytidine analogue that has both antiviral and anticancer activities. This minireview focuses on its underlying molecular mechanisms of suppressing viral life cycle and cancer cell growth and discusses applications of… read more here.
Keywords: oncology; anticancer therapeutic; advanced anticancer; fnc ... See more keywords
Selected Monocyclic Monoterpenes and Their Derivatives as Effective Anticancer Therapeutic Agents
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DOI: 10.3390/ijms22094763
Abstract: Terpenes—a diverse group of secondary metabolites—constitute the largest class of natural products abundant in almost every plant species. The properties of concrete terpenes and essential oils have been intensively studied due to their widespread use… read more here.
Keywords: monoterpenes derivatives; anticancer therapeutic; effective anticancer; monocyclic monoterpenes ... See more keywords
Anticancer Therapeutic Strategies Targeting p53 Aggregation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911023
Abstract: p53 is a tumor suppressor protein that is mutated in more than 50% of cancer cases. When mutated, it frequently results in p53 oncogenic gain of function (GOF), resulting in a greater tendency to aggregate… read more here.
Keywords: aggregation; anticancer therapeutic; therapeutic strategies; p53 aggregation ... See more keywords
The anticancer therapeutic potential of pyrimidine-sulfonamide hybrids.
Sign Up to like & getrecommendations! Published in 2024 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2024-0010
Abstract: Cancer as a devastating malignancy, seriously threatens human life and health, but most chemotherapeutics have long been criticized for unsatisfactory therapeutic efficacy due to drug resistance and severe off-target toxicity. Pyrimidines, including fused pyrimidines, are… read more here.
Keywords: hybrids anticancer; pyrimidine sulfonamide; sulfonamide hybrids; anticancer therapeutic ... See more keywords