α1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin-Sialyl LewisX Interaction.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0038-1675601
Abstract: BACKGROUND C1-inhibitor (C1-inh) therapeutics can reduce neutrophil activity in various inflammatory conditions. This 'novel' anti-inflammatory effect of C1-inh is attributed to the tetrasaccharide sialyl LewisX (SLeX) present on its N-glycans. Via SLeX, C1-inh is suggested… read more here.
Keywords: inh; inhibitor; act; antichymotrypsin ... See more keywords
Elevated plasma α1-antichymotrypsin is a biomarker candidate for malaria patients
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DOI: 10.5483/bmbrep.2022.55.11.126
Abstract: Advancements in the field of proteomics have provided opportunities to develop diagnostic and therapeutic strategies against various diseases. About half of the world’s population remains at risk of malaria. Caused by protozoan parasites of the… read more here.
Keywords: plasma samples; falciparum malaria; antichymotrypsin; malaria ... See more keywords