Tranexamic Acid Failed to Reverse the Anticoagulant Effect and Bleeding by an Oral Direct Factor Xa Inhibitor Edoxaban
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacology"
DOI: 10.1159/000484172
Abstract: Background/Aims: Agents to reverse the anticoagulant effect of edoxaban, an oral direct factor Xa inhibitor, would be desirable in emergency situations. The aim of this study is to determine the effect of tranexamic acid, an… read more here.
Keywords: anticoagulant effect; edoxaban; reverse anticoagulant; tranexamic acid ... See more keywords
Reversal of rivaroxaban anticoagulant effect by prothrombin complex concentrates: which dose is sufficient to restore normal thrombin generation?
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis Journal"
DOI: 10.1186/s12959-020-00228-9
Abstract: Rivaroxaban has the most available data to support the use of prothrombin complex concentrates (PCC) as a reversal agent. However, PCC might increase the incidence of thrombotic events by shifting the haemostatic balance towards hypercoagulability.… read more here.
Keywords: prothrombin complex; anticoagulant effect; complex concentrates; rivaroxaban anticoagulant ... See more keywords