Effect of a novel pharmacist-led reporting system on appropriate use of direct-acting oral anticoagulants (DOACs) in a patient-centered medical home
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02223-3
Abstract: Recent analyses demonstrate roughly 16–24% of patients taking direct-acting oral anticoagulants (DOACs) are prescribed an inappropriate dose, exposing patients to increased risk of thrombosis or bleeding. The use of reporting systems in the outpatient setting… read more here.
Keywords: acting oral; oral anticoagulants; effect novel; novel pharmacist ... See more keywords
Efficacy and safety of direct oral anticoagulants (DOACs) versus vitamin K antagonist (VKA) among patients with atrial fibrillation and hypertrophic cardiomyopathy: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Acta Cardiologica"
DOI: 10.1080/00015385.2019.1668113
Abstract: Abstract Background/objectives: Long-term oral anticoagulant therapy is recommended for patients with hypertrophic cardiomyopathy (HCM) who develop atrial fibrillation (AF) to prevent cardioembolic complications. In patients with non-valvular AF, direct oral anticoagulants (DOACs) has been proved… read more here.
Keywords: atrial fibrillation; oral anticoagulants; vka; hypertrophic cardiomyopathy ... See more keywords
Efficacy and safety of direct oral anticoagulants (DOACs) and low molecular weight heparin (LMWH) for primary prevention of venous thromboembolism (VTE) in ambulatory cancer patients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.12088
Abstract: 12088Background: Active malignancy is a well described risk factor for thrombosis. Randomized clinical trials (RCT) have evaluated anticoagulation (AC) with DOACs or LMWH for prevention of VTE in a... read more here.
Keywords: efficacy safety; oral anticoagulants; safety direct; direct oral ... See more keywords
Laboratory Monitoring or Measurement of Direct Oral Anticoagulants (DOACs): Advantages, Limitations and Future Challenges.
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DOI: 10.2174/1389200218666170417124035
Abstract: BACKGROUND The Direct Oral Anticoagulants (DOACs) represent a new generation of antithrombotic agents, providing direct inhibition of either thrombin (factor IIa; FIIa) or activated factor X (FXa). Around the globe, their use is progressively rising,… read more here.
Keywords: oral anticoagulants; direct oral; drug; measurement ... See more keywords
Direct Oral Anticoagulants (DOACs) for Therapeutic Targeting of Thrombin, a Key Mediator of Cerebrovascular and Neuronal Dysfunction in Alzheimer’s Disease
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DOI: 10.3390/biomedicines10081890
Abstract: Although preclinical research and observer studies on patients with atrial fibrillation concluded that direct oral anticoagulants (DOACs) can protect against dementia like Alzheimer’s disease (AD), clinical investigation towards therapeutical approval is still pending. DOACs target… read more here.
Keywords: alzheimer disease; direct oral; dysfunction; anticoagulants doacs ... See more keywords