Synthesis, anticonvulsant screening, and molecular modeling studies of new arylalkylimidazole oxime ether derivatives
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DOI: 10.1002/ddr.21491
Abstract: In this study, 15 new oxime ether derivatives were synthesized and their anticonvulsant activities were screened in vivo. The compounds were synthesized by the reaction of various alkyl halides with 1‐(2‐naphthyl)‐2‐(1H‐imidazol‐1‐yl)ethanone oxime. Their anticonvulsant activities… read more here.
Keywords: oxime; anticonvulsant screening; oxime ether; synthesis anticonvulsant ... See more keywords
The Anticonvulsant Screening Program of the National Institute of Neurological Disorders and Stroke, NIH: History and Contributions to Clinical Care in the Twentieth Century and Beyond
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DOI: 10.1007/s11064-017-2215-y
Abstract: The anticonvulsant screening program (ASP) of the national institute of neurological disorders and stroke (NINDS), National Institutes of Health has made substantial contributions to the drug armamentarium of the clinical neurologist. This program, originally a… read more here.
Keywords: national institute; screening program; anticonvulsant screening; program ... See more keywords