Magnetic micro-solid-phase extraction based on magnetite-MCM-41 with gas chromatography-mass spectrometry for the determination of antidepressant drugs in biological fluids.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700549
Abstract: A new facile magnetic micro-solid-phase extraction coupled to gas chromatography and mass spectrometry detection was developed for the extraction and determination of selected antidepressant drugs in biological fluids using magnetite-MCM-41 as adsorbent. The synthesized sorbent… read more here.
Keywords: gas chromatography; extraction; antidepressant drugs; determination ... See more keywords
Antidepressants, antimicrobials or both? Gut microbiota dysbiosis in depression and possible implications of the antimicrobial effects of antidepressant drugs for antidepressant effectiveness.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2016.09.012
Abstract: OBJECTIVES The first drug repurposed for the treatment of depression was the tuberculostatic iproniazid. At present, drugs belonging to new classes of antidepressants still have antimicrobial effects. Dysbiosis of gut microbiota was implicated in the… read more here.
Keywords: dysbiosis; depression; antimicrobial effects; antidepressant drugs ... See more keywords
Biophysical studies on the interactions between antidepressant drugs and bile salts
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2017.02.102
Abstract: Abstract The mechanism of the interaction of drugs with other foreign materials is of paramount importance in the drug delivery. The excess amount of drugs can cause overstimulation, psychotic illness and other disorders. In recent… read more here.
Keywords: biophysical studies; antidepressant drugs; drugs bile; studies interactions ... See more keywords
Decreased sensitivity to antidepressant drugs in Wistar Hannover rats submitted to two animal models of depression.
Sign Up to like & getrecommendations! Published in 2022 at "Acta neuropsychiatrica"
DOI: 10.1017/neu.2022.24
Abstract: The Wistar Hannover rat (WHR) is a strain commonly used for toxicity studies but rarely used in studies investigating depression neurobiology. In this study, we aimed to characterise the behavioural responses of WHR to acute… read more here.
Keywords: whr; depression; antidepressant drugs; test ... See more keywords
Relative frequency of drug-induced sleep disorders for 32 antidepressants in a large set of Internet user reviews.
Sign Up to like & getrecommendations! Published in 2021 at "Sleep"
DOI: 10.1093/sleep/zsab174
Abstract: STUDY OBJECTIVES It is known that antidepressant drugs can induce sleep disorders in patients, but little data exist about high or low-risk molecules. The aim was to study the frequency of antidepressant drugs-induced sleep disorders… read more here.
Keywords: antidepressant drugs; disd prr; frequency; induced sleep ... See more keywords
Repositioning or Redirection of Antidepressant Drugs in the Treatment of Bacterial and Fungal Infections.
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Therapeutics"
DOI: 10.1097/mjt.0000000000001001
Abstract: increases in temperature produced by MPD could trigger compensatory cooling mechanisms, which would explain the increased yawn frequency. Moreover, the abrupt and complete eradication of yawning after the discontinuation of MPD and introduction of atomoxetine… read more here.
Keywords: redirection antidepressant; drugs treatment; treatment; antidepressant drugs ... See more keywords
The use of antidepressant drugs in pregnant women with epilepsy: A study from the Australian Pregnancy Register
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsia"
DOI: 10.1111/epi.14539
Abstract: To study interactions between first‐trimester exposure to antidepressant drugs (ADDs) and antiepileptic drugs (AEDs), and a history of clinical depression and/or anxiety, on pregnancy outcomes and seizure control in pregnant women with epilepsy (WWE). read more here.
Keywords: pregnancy; antidepressant drugs; pregnant women; study ... See more keywords
Therapeutic Effect of Novel Antidepressant Drugs Acting at Specific Receptors of Neurotransmitters and Neuropeptides.
Sign Up to like & getrecommendations! Published in 2019 at "Current pharmaceutical design"
DOI: 10.2174/1381612825666190410165243
Abstract: BACKGROUND Major depression is a frequent psychiatric disease. One- third of the depressive patients remain treatment-resistant; thus, it is urgent to find novel antidepressant drugs. OBJECTIVE In major depression, in several brain areas the neural… read more here.
Keywords: receptor antagonist; antidepressant drugs; neurotransmitters neuropeptides; effect ... See more keywords
Classical hallucinogens as antidepressant drugs: A cautionary approach.
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x20666220425133824
Abstract: read more here.
Keywords: hallucinogens antidepressant; classical hallucinogens; antidepressant drugs; drugs cautionary ... See more keywords
Influence of antidepressant drugs on DNA methylation of ion channels genes in blood cells of psychiatric patients.
Sign Up to like & getrecommendations! Published in 2022 at "Epigenomics"
DOI: 10.2217/epi-2022-0089
Abstract: Aim: This study investigated the influence of antidepressant drugs on methylation status of KCNE1, KCNH2 and SCN5A promoters and ECG parameters in adult psychiatric patients. Materials & methods: Electrocardiographic evaluation (24 h) and blood samples were… read more here.
Keywords: methylation; dna methylation; antidepressant drugs; psychiatric patients ... See more keywords
Comorbid epilepsy and depression—pharmacokinetic and pharmacodynamic drug interactions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.988716
Abstract: Background: Major depressive disorder may be encountered in 17% of patients with epilepsy and in patients with drug-resistant epilepsy its prevalence may reach 30%. This indicates that patients with epilepsy may require antidepressant treatment. Purpose:… read more here.
Keywords: depression pharmacokinetic; pharmacology; antidepressant drugs; comorbid epilepsy ... See more keywords