LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "antidepressant effect" as a keyword



The antidepressant effect of Shexiang Baoxin Pills on myocardial infarction rats with depression may be achieved through the inhibition of the NLRP3 inflammasome pathway

Sign Up to like & get
recommendations! Published in 2024 at "Brain and Behavior"

DOI: 10.1002/brb3.3586

Abstract: Patients with myocardial infarction (MI) frequently experience a heightened incidence of depression, thereby increasing the risk of adverse cardiovascular events. Consequently, early detection and intervention in depressive symptoms among patients with MI are imperative. Shexiang… read more here.

Keywords: baoxin pills; infarction; shexiang baoxin; myocardial infarction ... See more keywords

NMDA receptor antagonists traxoprodil and lanicemine improve hippocampal-prefrontal coupling and reward-related networks in rats

Sign Up to like & get
recommendations! Published in 2019 at "Psychopharmacology"

DOI: 10.1007/s00213-019-05310-3

Abstract: RationaleThe N-methyl-d-aspartate receptor (NMDAR) antagonist ketamine is known to have not only a rapid antidepressant effect but also dissociative side effects. Traxoprodil and lanicemine, also NMDA antagonists, are candidate antidepressant drugs with fewer side effects.ObjectivesIn… read more here.

Keywords: ketamine; connectivity; antidepressant effect; effect ... See more keywords
Photo from wikipedia

Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects

Sign Up to like & get
recommendations! Published in 2021 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2021.108679

Abstract: BACKGROUND AND PURPOSE Although useful as a rapid-acting antidepressant drug, ketamine is known to induce psychotomimetic effects, which may interfere with its therapeutic use. Cannabidiol (CBD) is a non-psychostimulant compound from Cannabis sativa, which has… read more here.

Keywords: cbd; ketamine; effect; antidepressant effect ... See more keywords
Photo from wikipedia

Volume of hippocampal subregions and clinical improvement following electroconvulsive therapy in patients with depression

Sign Up to like & get
recommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"

DOI: 10.1016/j.pnpbp.2020.110048

Abstract: It is thought that the hippocampal neurogenesis is an important mediator of the antidepressant effect of electroconvulsive therapy (ECT). However, most previous studies failed to demonstrate the relationship between the increase in the hippocampal volume… read more here.

Keywords: depression; volume; hippocampal subregions; clinical improvement ... See more keywords

Antidepressant Effect of Ketamine on Inflammation-Mediated Cytokine Dysregulation in Adults with Treatment-Resistant Depression: Rapid Systematic Review

Sign Up to like & get
recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/1061274

Abstract: Background Major depressive disorder (MDD) and treatment-resistant depression (TRD) represent a global source of societal and health burden. To advise proper management of inflammation-related depression among TRD patients, it is important to identify therapeutic clinical… read more here.

Keywords: trd patients; ketamine; depression; antidepressant effect ... See more keywords

Suggestive Evidence for an Antidepressant Effect of Metreleptin Treatment in Patients with Lipodystrophy

Sign Up to like & get
recommendations! Published in 2022 at "Obesity Facts"

DOI: 10.1159/000526357

Abstract: Introduction: Lipodystrophy (LD) syndromes are rare heterogeneous disorders characterized by reduction or absence of subcutaneous fat, low or nondetectable leptin concentrations in blood and impaired hunger/satiety regulation. Metreleptin treatment reverses metabolic complications and improves eating… read more here.

Keywords: treatment; antidepressant effect; depression; metreleptin treatment ... See more keywords

Antidepressant Effect and Recognition Memory Improvement of Two Novel Plant Extract Combinations - Antistress I and Anti-stress II on Rats Subjected to a Model of Mild Chronic Stress

Sign Up to like & get
recommendations! Published in 2018 at "Folia Medica"

DOI: 10.1515/folmed-2017-0073

Abstract: Abstract Background: Chronic stress is one of the main factors which lead to depression – a psychiatric disorder affecting millions of people and predicted to be the second ranked cause of premature death in 2020.… read more here.

Keywords: antidepressant effect; recognition memory; stress; memory ... See more keywords

Salmon Calcitonin Exerts an Antidepressant Effect by Activating Amylin Receptors

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.826055

Abstract: Depressive disorder is defined as a psychiatric disease characterized by the core symptoms of anhedonia and learned helplessness. Currently, the treatment of depression still calls for medications with high effectiveness, rapid action, and few side… read more here.

Keywords: amylin; antidepressant effect; salmon calcitonin; amylin receptors ... See more keywords

Integration of Non-Targeted Metabolomics and Targeted Quantitative Analysis to Elucidate the Synergistic Antidepressant Effect of Bupleurum Chinense DC-Paeonia Lactiflora Pall Herb Pair by Regulating Purine Metabolism

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.900459

Abstract: Graphical Abstract Bupleurum chinense DC (Chaihu)-Paeonia lactiflora Pall (Baishao) is among the most accepted herb pairs in many classic antidepressant prescriptions. Our previous study has shown that the Chaihu–Baishao herb pair (CBHP) had a better… read more here.

Keywords: effect; purine metabolism; antidepressant effect; analysis ... See more keywords
Photo from wikipedia

Serotonergic psychedelics for depression: What do we know about neurobiological mechanisms of action?

Sign Up to like & get
recommendations! Published in 2023 at "Frontiers in Psychiatry"

DOI: 10.3389/fpsyt.2022.1076459

Abstract: Introduction Current treatment options for major depressive disorder (MDD) have limited efficacy and are associated with adverse effects. Recent studies investigating the antidepressant effect of serotonergic psychedelics—also known as classic psychedelics—have promising preliminary results with… read more here.

Keywords: action serotonergic; action; antidepressant effect; serotonergic psychedelics ... See more keywords

Baicalin Ameliorates Depression-like Behaviors via Inhibiting Neuroinflammation and Apoptosis in Mice

Sign Up to like & get
recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms251910259

Abstract: Depression is a common neuropsychiatric disease which brings an increasing burden to all countries globally. Baicalin, a flavonoid extracted from the dried roots of Scutellaria, has been reported to exert anti-inflammatory, antioxidant, and neuroprotective effects… read more here.

Keywords: baicalin; analysis; depression; antidepressant effect ... See more keywords