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Published in 2022 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2022.03.057
Abstract: Tricyclic antidepressants (TCAs) are frequently prescribed in case of non-response to first-line antidepressants in Major Depressive Disorder (MDD). Treatment of MDD often entails a trial-and-error process of finding a suitable antidepressant and its appropriate dose.…
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Keywords:
major depressive;
response;
tricyclic antidepressants;
antidepressants major ... See more keywords
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Published in 2025 at "Pharmaceuticals"
DOI: 10.3390/ph18091360
Abstract: Purpose: Genetic polymorphisms within specific genes play a role in both the genetic predisposition to Major Depressive Disorder (MDD) and the variation observed in responses to antidepressant treatments. Pharmacogenetics examines how these polymorphisms affect medication…
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Keywords:
treatment;
antidepressants major;
depressive disorder;
response ... See more keywords