Repurposing Antidepressants and Phenothiazine Antipsychotics as Efflux Pump Inhibitors in Cancer and Infectious Diseases
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DOI: 10.3390/antibiotics12010137
Abstract: Multidrug resistance (MDR) is a major obstacle in the therapy of infectious diseases and cancer. One of the major mechanisms of MDR is the overexpression of efflux pumps (EPs) that are responsible for extruding antimicrobial… read more here.
Keywords: infectious diseases; phenothiazine antipsychotics; development; repurposing antidepressants ... See more keywords