Antioxidative potential of antidiabetic agents: A possible protective mechanism against vascular complications in diabetic patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27278
Abstract: Many vascular complications are related to exposure of tissues to elevated levels of glucose, a condition that promotes oxidative stress. The primary goal of antidiabetic medication is for normalization of blood glucose. However, antidiabetic medications… read more here.
Keywords: agents possible; possible protective; potential antidiabetic; vascular complications ... See more keywords
Insight in the safety profile of antidiabetic agents glucagon‐like peptide‐1 agonists and dipeptidyl peptidase‐4 inhibitors in daily practice from the patient perspective
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5077
Abstract: The primary aim of this study was to gain insight in the safety profile of the new antidiabetic agents glucagon‐like peptide‐1 (GLP‐1) agonists and dipeptidyl peptidase‐4 (DPP‐4) inhibitors in daily practice. The secondary aim was… read more here.
Keywords: safety profile; safety; insight safety; practice ... See more keywords
Design, synthesis, docking and biological evaluation of chalcones as promising antidiabetic agents.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103527
Abstract: Diabetes mellitus (DM) is a serious chronic metabolic disorder which occurs due to dysfunction of insulin and therapeutic approaches are poor. It is an under estimation that 387 million people currently suffering globally with diabetic… read more here.
Keywords: design synthesis; synthesis docking; biological evaluation; evaluation chalcones ... See more keywords
Oral Antidiabetic Agents and Cardiovascular Outcomes.
Sign Up to like & getrecommendations! Published in 2018 at "Current problems in cardiology"
DOI: 10.1016/j.cpcardiol.2017.07.003
Abstract: Cardiovascular disease is the leading cause of morbidity and mortality among patients with type 2 diabetes; however, a direct protective effect of tight glycemic control remains unproven. In fact, until 2008, when concerns related to… read more here.
Keywords: antidiabetic agents; agents cardiovascular; oral antidiabetic; cardiovascular outcomes ... See more keywords
Antidiabetic drugs and stroke risk. Current evidence.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2017.09.019
Abstract: Cardiovascular disease (CVD) is the major cause of morbidity and mortality for individuals with type 2 diabetes (T2D). In particular, the risk for stroke is twice that of patients without diabetes, and diabetes may be… read more here.
Keywords: antidiabetic drugs; risk; stroke risk; evidence ... See more keywords
Thiazolidinediones and PPAR orchestra as antidiabetic agents: From past to present.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2016.12.020
Abstract: Thiazolidinediones a class of drug, that provided a major breakthrough in the management of type 2 diabetes since 1990. Following the discovery of PPARs, TZDs were the first class to be reported as PPARγ modulators.… read more here.
Keywords: thiazolidinediones ppar; agents past; linker; ppar orchestra ... See more keywords
An investigation of physicians' prescribing behaviors related to antidiabetic agents for Type 2 diabetes mellitus patients and associated factors in Taiwan
Sign Up to like & getrecommendations! Published in 2022 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2022.2105539
Abstract: Abstract Objectives This study aimed to examine the factors that may influence physicians’ choice of antidiabetic agents. In addition, we investigated physicians’ decision-making process and treatment of T2DM patients with chronic kidney disease (CKD). Finally,… read more here.
Keywords: prescribing behaviors; investigation physicians; behaviors related; physicians prescribing ... See more keywords
The potential effects of clinical antidiabetic agents on SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.13135
Abstract: Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2), is currently posing significant threats to public health worldwide. It is notable that a substantial proportion of patients with sever COVID‐19 have coexisting… read more here.
Keywords: clinical antidiabetic; effects clinical; agents sars; potential effects ... See more keywords
Comparative efficacy and acceptability of antidiabetic agents for Alzheimer's disease and mild cognitive impairment: A systematic review and network meta‐analysis
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes"
DOI: 10.1111/dom.13373
Abstract: This study (registered with PROSPERO, CRD42018085967) compares the efficacy (i.e. pro‐cognitive effects) and acceptability of antidiabetic agents for Alzheimer's disease (AD) and mild cognitive impairment (MCI). Cochrane Library (CENTRAL), PubMed/MEDLINE, EMBASE and PsycINFO were searched… read more here.
Keywords: acceptability; alzheimer disease; agents alzheimer; acceptability antidiabetic ... See more keywords
A Review of the Renoprotective Effects of Novel Antidiabetic Agents
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pharmacy Practice"
DOI: 10.1177/0897190020902344
Abstract: The objective of this review article was to identify and examine current evidence surrounding the potential renoprotective effects of newer antidiabetic agents such as sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucose-like peptide 1 (GLP-1) agonists, and… read more here.
Keywords: review renoprotective; sglt inhibitors; renoprotective effects; inhibitors glp ... See more keywords
Structure and function analysis of adiponectin receptors toward development of novel antidiabetic agents promoting healthy longevity.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine journal"
DOI: 10.1507/endocrj.ej18-0310
Abstract: Plasma adiponectin levels and expression of its receptors, AdipoRs are decreased in obesity, which cause insulin resistance and diabetes. AdipoR-deficient mice exhibit insulin resistance and impaired glucose tolerance. Moreover, newly identified AdipoR agonists not only… read more here.
Keywords: novel; development novel; adiponectin; structure ... See more keywords