Unveiling the research directions for pyrrolidine-based small molecules as versatile antidiabetic and anticancer agents.
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DOI: 10.1080/17568919.2025.2501923
Abstract: The pyrrolidine moiety, a five-membered saturated nitrogen-containing heterocycle, emerged as a crucial pharmacophore in medicinal chemistry due to its distinctive physicochemical properties, including hydrophilicity, basicity, and structural rigidity. Extensive modifications of pyrrolidine derivatives yielded novel… read more here.
Keywords: pyrrolidine based; chemistry; antidiabetic anticancer; versatile antidiabetic ... See more keywords