Butyrate‐Mediated Upregulation of Insulin Pathway Gene Expression Suggests Potential Antidiabetic Effects
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development Research"
DOI: 10.1002/ddr.70203
Abstract: Type 2 diabetes (T2D) is a major cause of morbidity in developed countries and involves insulin resistance, a failure to correctly respond to insulin. Numerous studies in rodent T2D models suggested that the short‐chain fatty… read more here.
Keywords: antidiabetic effects; insulin; effects butyrate; expression ... See more keywords
Antidiabetic effects of different polysaccharide fractions from Artemisia sphaerocephala Krasch seeds in db/db mice
Sign Up to like & getrecommendations! Published in 2019 at "Food Hydrocolloids"
DOI: 10.1016/j.foodhyd.2019.01.002
Abstract: Abstract Artemisia sphaerocephala Krasch polysaccharide (ASKP) has previously been reported to ameliorate the hyperglycemia and oxidative stress in type 2 diabetes mellitus and was separated into two fractions of 60P and 60S. To determine the… read more here.
Keywords: sphaerocephala krasch; mice; antidiabetic effects; artemisia sphaerocephala ... See more keywords
Antidiabetic effects of SGLT2 inhibitor ipragliflozin in type 2 diabetic mice fed diets containing different carbohydrate contents
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DOI: 10.1016/j.lfs.2018.02.009
Abstract: Aims: Daily intake of carbohydrates differs among individual patients with type 2 diabetes. Here, we investigated whether or not dietary carbohydrate content affects the efficacy of the sodium‐glucose cotransporter 2 (SGLT2) inhibitor ipragliflozin in type… read more here.
Keywords: ipragliflozin; sglt2 inhibitor; carbohydrate; diabetic mice ... See more keywords
Preparation of S-Allylcysteine-Enriched Black Garlic Juice and Its Antidiabetic Effects in Streptozotocin-Induced Insulin-Deficient Mice.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.6b04948
Abstract: S-Allylcysteine (SAC), produced in large amounts during the aging process of garlic via enzymatic hydrolysis, is known as a key compound responsible for the multiple pharmacological activities of aged black garlic. This study investigated the… read more here.
Keywords: garlic juice; aging process; black garlic; allylcysteine ... See more keywords
Anti-obesogenic and antidiabetic effects of plants and mushrooms
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Endocrinology"
DOI: 10.1038/nrendo.2016.142
Abstract: Obesity is reaching global epidemic proportions as a result of factors such as high-calorie diets and lack of physical exercise. Obesity is now considered to be a medical condition, which not only contributes to the… read more here.
Keywords: obesogenic antidiabetic; plants mushrooms; effects plants; anti obesogenic ... See more keywords
Antidiabetic Effects and Underlying Mechanisms of Food-Derived Bioactive Peptides.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal food"
DOI: 10.1089/jmf.2024.0018
Abstract: Type 2 diabetes mellitus (T2DM), characterized by progressive insulin secretion defect based on insulin resistance, is one of the leading public health problems with high morbidity and mortality rates. Uncontrolled hyperglycemia, which becomes a more… read more here.
Keywords: bioactive peptides; food derived; food; antidiabetic effects ... See more keywords
Antioxidant and antidiabetic effects of Flemingia macrophylla leaf extract and fractions: In vitro, molecular docking, dynamic simulation, pharmacokinetics, and biological activity studies
Sign Up to like & getrecommendations! Published in 2024 at "BioResources"
DOI: 10.15376/biores.19.3.4960-4983
Abstract: Flemingia macrophylla has traditionally been applied to relieve inflammation, diabetes, and circulatory complications. The leaf extract of F. macrophylla and its fractions were investigated for their in-vitro antioxidant and anti-diabetic properties. The phytochemical screening showed… read more here.
Keywords: antidiabetic effects; antioxidant antidiabetic; macrophylla; leaf extract ... See more keywords
The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice.
Sign Up to like & getrecommendations! Published in 2022 at "Cell metabolism"
DOI: 10.2139/ssrn.3929011
Abstract: Low-grade, sustained inflammation in white adipose tissue (WAT) characterizes obesity and coincides with type 2 diabetes mellitus (T2DM). However, pharmacological targeting of inflammation lacks durable therapeutic effects in insulin-resistant conditions. Through a computational screen, we… read more here.
Keywords: drug auranofin; leptin levels; rheumatoid arthritis; antidiabetic effects ... See more keywords
Antidiabetic effects of Tetracarpidium conophorum seed on biomarkers of diabetes-induced nephropathy in rats
Sign Up to like & getrecommendations! Published in 2018 at "Asian Pacific Journal of Tropical Biomedicine"
DOI: 10.4103/2221-1691.248096
Abstract: Objective: To investigate antidiabetic effects of Tetracarpidium conophorum seed (TECOSE) against biomarkers of diabetes-induced nephropathy in rats. Methods: Powdered seed (500 g) of TECOSE was extracted with 5 L of 100% methanol for 72 h… read more here.
Keywords: seed; nephropathy rats; diabetes induced; body weight ... See more keywords