Protein engineering of antifreeze proteins reveals that their activity scales with the area of the ice‐binding site
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14552
Abstract: Antifreeze proteins (AFPs) protect organisms from freezing by binding to ice crystals to prevent their growth. Here, we have investigated how the area of an AFP's ice‐binding site (IBS) changes its antifreeze activity. The polyproline… read more here.
Keywords: antifreeze; area; activity; antifreeze proteins ... See more keywords
Mimicking the Ice Recrystallization Activity of Biological Antifreezes. When is a New Polymer “Active”?
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201900082
Abstract: Antifreeze proteins and ice-binding proteins have been discovered in a diverse range of extremophiles and have the ability to modulate the growth and formation of ice crystals. Considering the importance of cryoscience across transport, biomedicine,… read more here.
Keywords: antifreeze proteins; recrystallization activity; mimicking ice; ice recrystallization ... See more keywords
AFP-SRC: identification of antifreeze proteins using sparse representation classifier
Sign Up to like & getrecommendations! Published in 2022 at "Neural Computing and Applications"
DOI: 10.1007/s00521-021-06558-7
Abstract: Species living in the extreme cold environment fight against the harsh conditions using antifreeze proteins (AFPs), which manipulate the freezing mechanism of water in more than one way. This amazing nature of AFPs turns out… read more here.
Keywords: src identification; using sparse; afp src; antifreeze proteins ... See more keywords
A brief review of applications of antifreeze proteins in cryopreservation and metabolic genetic engineering
Sign Up to like & getrecommendations! Published in 2019 at "3 Biotech"
DOI: 10.1007/s13205-019-1861-y
Abstract: Antifreeze proteins (AFPs) confer the ability to survive at subzero temperatures and are found in many different organisms, including fish, plants, and insects. They prevent the formation of ice crystals by non-colligative adsorption to the… read more here.
Keywords: insects; antifreeze proteins; metabolic genetic; cryopreservation ... See more keywords
The properties, biotechnologies, and applications of antifreeze proteins.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.03.040
Abstract: By natural selection, organisms evolve different solutions to cope with extremely cold weather. The emergence of an antifreeze protein gene is one of the most momentous solutions. Antifreeze proteins possess an importantly functional ability for… read more here.
Keywords: biotechnologies applications; antifreeze proteins; properties biotechnologies; applications antifreeze ... See more keywords
Ice Recrystallization Inhibition Is Insufficient to Explain Cryopreservation Abilities of Antifreeze Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c01477
Abstract: Antifreeze proteins (AFPs) and glycoproteins (AFGPs) are exemplary at modifying ice crystal growth and at inhibiting ice recrystallization (IRI) in frozen solutions. These properties make them highly attractive for cold storage and cryopreservation applications of… read more here.
Keywords: insufficient explain; iri; antifreeze proteins; ice recrystallization ... See more keywords
AFP-SPTS: An Accurate Prediction of Antifreeze Proteins Using Sequential and Pseudo-Tri-Slicing Evolutionary Features with an Extremely Randomized Tree
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c01417
Abstract: The development of intracellular ice in the bodies of cold-blooded living organisms may cause them to die. These species yield antifreeze proteins (AFPs) to live in subzero temperature environments. Additionally, AFPs are implemented in biotechnological,… read more here.
Keywords: extremely randomized; prediction; antifreeze proteins; randomized tree ... See more keywords
Molecular Recognition of Ice by Fully Flexible Molecules
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Physical Chemistry C"
DOI: 10.1021/acs.jpcc.7b10265
Abstract: Cold acclimatized organisms produce antifreeze proteins that prevent ice growth and recrystallization at subfreezing conditions. Flatness and rigidity of the ice-binding sites of antifreeze proteins are considered key for their recognition of ice. However, the… read more here.
Keywords: recognition ice; antifreeze proteins; fully flexible; pva ... See more keywords
AFP-LSE: Antifreeze Proteins Prediction Using Latent Space Encoding of Composition of k-Spaced Amino Acid Pairs
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63259-2
Abstract: Species living in extremely cold environments resist the freezing conditions through antifreeze proteins (AFPs). Apart from being essential proteins for various organisms living in sub-zero temperatures, AFPs have numerous applications in different industries. They possess… read more here.
Keywords: antifreeze proteins; prediction; using latent; latent space ... See more keywords
Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles† †Electronic supplementary information (ESI) available: Synthetic and analytical details. See DOI: 10.1039/c8py01719k
Sign Up to like & getrecommendations! Published in 2019 at "Polymer Chemistry"
DOI: 10.1039/c8py01719k
Abstract: Antifreeze proteins are site-specifically conjugated onto polymer-stabilised gold nanoparticles, resulting in hybrid materials capable of modulating ice growth processes. read more here.
Keywords: site specific; antifreeze proteins; onto polymer;
Nanoscopy of single antifreeze proteins reveals that reversible ice binding is sufficient for ice recrystallization inhibition but not thermal hysteresis.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212456120
Abstract: Antifreeze proteins (AFPs) bind ice to reduce freezing temperatures and arrest ice crystal ripening, making AFPs essential for the survival of many organisms in ice-laden environments and attractive as biocompatible antifreezes in many applications. While… read more here.
Keywords: ice; recrystallization inhibition; activity; antifreeze proteins ... See more keywords