Synthesis and evaluation of alpha-Ag2WO4 as novel antifungal agent
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Physics Letters"
DOI: 10.1016/j.cplett.2017.02.067
Abstract: Abstract Because of the need for new antifungal materials with greater potency, microcrystals of α-Ag2WO4, a complex metal oxide, have been synthetized by a simple co-precipitation method, and their antifungal activity against Candida albicans has… read more here.
Keywords: novel antifungal; ag2wo4 novel; antifungal agent; alpha ag2wo4 ... See more keywords
Development and Validation of a LC-MS/MS Method for the Profiling of Impurities Formed during Stress Study of Antifungal Agent-Efinaconazole.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmab079
Abstract: Liquid chromatography interfaced with mass spectroscopy (LC-MS) is a sensitive and effective analytical method that combines high-resolution separation as well as specific mass detection of impurities in formulated products and as well as in active… read more here.
Keywords: impurities formed; antifungal agent; study; method ... See more keywords
The Use of Dietary Antifungal Agent Terbinafine in Artificial Diet and Its Effects on Some Biological and Biochemical Parameters of the Model Organism Galleria mellonella (Lepidoptera: Pyralidae)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Economic Entomology"
DOI: 10.1093/jee/toaa039
Abstract: Abstract Diet quality widely affects the survival, development, fecundity, longevity, and hatchability of insects. We used the greater wax moth Galleria mellonella (Linnaeus) to determine the effects of the antifungal, antibiotic terbinafine on some of… read more here.
Keywords: use; antifungal agent; galleria mellonella; effects biological ... See more keywords
The solid-state conformation of the topical antifungal agent O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate
Sign Up to like & getrecommendations! Published in 2018 at "Acta Crystallographica. Section C, Structural Chemistry"
DOI: 10.1107/s2053229618013591
Abstract: Large flat colorless needles of tolnaftate have been obtained from Tinactin, and have been shown to contain a 50:50 mixture of the (+ap,−sp,+ac,−ac) and (−ap,+sp,−ac,+ac) conformers. This finding fills a long-standing void in the structural… read more here.
Keywords: solid state; conformation topical; antifungal agent; chemistry ... See more keywords
Progress of triazole antifungal agent posaconazole in individualized therapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13821
Abstract: Posaconazole is the second‐generation triazole antifungal agent with widespread clinical application. Posaconazole exposure is influenced by various factors such as drug interactions, disease state and diet, resulting in a high interindividual variability in many patients… read more here.
Keywords: triazole antifungal; individualized therapy; antifungal agent; posaconazole ... See more keywords
Impact of Indazole scaffold as Antibacterial and Antifungal agent.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220512145646
Abstract: Heterocycles consisting of nitrogen atom, Indazole, is a pungent, biological, heterocyclic, bicyclic compounds possessing electron rich portions. Indazole composed of two nitrogen atoms put under the azoles family, further called as isoindazolone. It is a… read more here.
Keywords: impact indazole; antifungal agent; scaffold antibacterial; antibacterial antifungal ... See more keywords
Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2018.00164
Abstract: Antifungal agents for the treatment of Candida albicans infections are limited. We recently discovered a novel antifungal small molecule, SM21, with promising in vivo activity. Herein, we employed the newly developed C. albicans haploid toolbox… read more here.
Keywords: novel antifungal; uncover mechanism; sm21; antifungal agent ... See more keywords
Potential of Gallium as an Antifungal Agent
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00414
Abstract: There are only few drugs available to treat fungal infections, and the lack of new antifungals, along with the emergence of drug-resistant strains, results in millions of deaths/year. An unconventional approach to fight microbial infection… read more here.
Keywords: antifungal agent; effect; gallium; gallium antifungal ... See more keywords
GR-2397: Review of the Novel Siderophore-like Antifungal Agent for the Treatment of Invasive Aspergillosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8090909
Abstract: GR-2397 (previously VL-2397, ASP2397) is a first-in-class antifungal agent for the treatment of invasive aspergillosis. This siderophore-like molecule resembles ferrichrome; however, it is differentiated by three amino acid changes and an aluminum rather than iron… read more here.
Keywords: agent treatment; antifungal agent; treatment invasive; treatment ... See more keywords
Bioactive Propolis-Silane System as Antifungal Agent in Lignocellulosic-Polymer Composites
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15103435
Abstract: Polymer composites with renewable lignocellulosic fillers, despite their many advantages, are susceptible to biodegradation, which is a major limitation in terms of external applications. The work uses an innovative hybrid propolis-silane modifier in order to… read more here.
Keywords: system; polymer composites; antifungal agent; polymer ... See more keywords
Repurposing Disulfiram as an Antifungal Agent: Development of a New Disulfiram Vaginal Mucoadhesive Gel
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15051436
Abstract: Alternative formulations need to be developed to improve the efficacy of treatments administered via the vaginal route. Mucoadhesive gels with disulfiram, a molecule that was originally approved as an antialcoholism drug, offer an attractive alternative… read more here.
Keywords: antifungal agent; development new; disulfiram antifungal; agent development ... See more keywords