Tinea in the Time Before Modern Antifungal Agents.
Sign Up to like & getrecommendations! Published in 2017 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2017.1545
Abstract: Modernity enjoys a broad and effective arsenal against superficial mycoses. However, the history of social stigma attached to dermatophyte infections, their unusual and often harmful treatments, and the controversial public health efforts designed to limit… read more here.
Keywords: antifungal agents; treatment; tinea; tinea capitis ... See more keywords
Natural products in crop protection: thiosemicarbazone derivatives of 3-acetyl-N-benzylindoles as antifungal agents and their mechanism of action.
Sign Up to like & getrecommendations! Published in 2023 at "Pest management science"
DOI: 10.1002/ps.7457
Abstract: BACKGROUND Phytopathogenic fungi can cause a direct loss in economic value of agriculture. Especially Valsa mali Miyabe et Yamada, a devastating phytopathogenic disease especially threatening global apple production, is very difficult to control and manage.… read more here.
Keywords: thiosemicarbazone derivatives; thiosemicarbazone; acetyl benzylindoles; mechanism action ... See more keywords
Animal Infections: The Role of Fungal Biofilms
Sign Up to like & getrecommendations! Published in 2019 at "Fungal Biology"
DOI: 10.1007/978-3-030-18586-2_10
Abstract: A biofilm is defined as adherent microbial communities on biotic or abiotic surfaces surrounded by extracellular polymeric substances (EPS) matrix. Biofilm formation by bacteria is very common; however, the pathogenic filamentous fungi and yeast also… read more here.
Keywords: antifungal agents; spp; animal infections; fungal biofilms ... See more keywords
Storability at room temperature of Steinernema yirgalemense (Rhabditida: Steinernematidae) in diatomaceous earth and the effect of antifungal agents
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Plant Diseases and Protection"
DOI: 10.1007/s41348-021-00521-3
Abstract: The commercial use of entomopathogenic nematodes after mass production requires the development of formulation techniques that extend nematode survival and prevent virulence loss during storage. In this study, the room temperature viability of Steinernema yirgalemense… read more here.
Keywords: effect antifungal; room temperature; diatomaceous earth; antifungal agents ... See more keywords
Design, synthesis, and in vitro evaluation of novel triazole analogues featuring isoxazole moieties as antifungal agents.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103982
Abstract: In order to develop novel antifungal agents, based on our previous work, a series of (2R,3R)-3-((3-substitutied-isoxazol-5-yl)methoxy)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl) butan-2-ol (a1-a26) were designed and synthesized. All of the compounds exhibited good in vitro antifungal activities against eight human… read more here.
Keywords: design synthesis; antifungal agents; evaluation novel; vitro evaluation ... See more keywords
Our pursuit for effective antifungal agents targeting fungal cell wall components, where are we?
Sign Up to like & getrecommendations! Published in 2021 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2021.106477
Abstract: Invasive mycotic infections account for an unacceptably high mortality rates in humans. These infections are initiated by the fungal cell wall which mediates host-fungi interactions. The cell wall is fused to the physiology of fungi,… read more here.
Keywords: pursuit effective; antifungal agents; fungal cell; cell wall ... See more keywords
Design, Synthesis, and Structure-Activity Relationship Studies of Magnolol Derivatives as Antifungal Agents.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c01838
Abstract: Plant pathogenic fungi seriously affect agricultural production and are difficult to control. The discovery of new leads based on natural products is an important way to innovate fungicides. In this study, 30 natural-product-based magnolol derivatives… read more here.
Keywords: antifungal agents; magnolol derivatives; activity relationship; structure activity ... See more keywords
Discovery of Novel Benzoxaborole-Containing Streptochlorin Derivatives as Potential Antifungal Agents.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c08053
Abstract: Streptochlorin is a kind of indole alkaloid derived from marine microorganisms. It is a promising lead compound due to its potent bioactivity in preventing many phytopathogens, as shown in our previous study. To explore the… read more here.
Keywords: compound; benzoxaborole containing; containing streptochlorin; streptochlorin derivatives ... See more keywords
Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01299
Abstract: Due to the increased morbidity and mortality by fungal infections and the emergence of severe antifungal resistance, there is an urgent need for new antifungal agents. Here, we screened for antifungal activity in our in-house… read more here.
Keywords: novel antifungal; antifungal agents; evaluation novel; optimization evaluation ... See more keywords
Synthesis of Benzimidazole-1,2,4-triazole Derivatives as Potential Antifungal Agents Targeting 14α-Demethylase
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c07755
Abstract: Invasive fungal infections (IFIs) are increasing as major infectious diseases around the world, and the limited efficacy of existing medications has resulted in substantial morbidity and death in patients due to the lack of effective… read more here.
Keywords: benzimidazole triazole; triazole derivatives; targeting demethylase; synthesis benzimidazole ... See more keywords
Phosphonium-based ionic liquids as antifungal agents for conservation of heritage sandstone
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra09169g
Abstract: With a view to preventing fungal deterioration of historical stone artworks, we report the use of phosphonium-based ionic liquids (ILs) as potent antifungal agents against dematiaceous fungi commonly found on heritage stones. Three ILs: tributyldodecylphosphonium… read more here.
Keywords: pom; phosphonium based; heritage sandstone; ionic liquids ... See more keywords