Impact of environmental factors on Streptomyces spp. metabolites against Botrytis cinerea
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.202100423
Abstract: Botrytis cinerea is an economically important disease on numerous vegetables including tomato. From our previous studies, a spore suspension of Streptomyces philanthi RL‐1‐178 and RM‐1‐138 and Streptomyces mycarofaciens SS‐2‐243 showed strong inhibition against B. cinerea.… read more here.
Keywords: antifungal compounds; streptomyces spp; light dark; botrytis cinerea ... See more keywords
Novel antifungal agents: a patent review (2013 - present)
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Therapeutic Patents"
DOI: 10.1080/13543776.2017.1261113
Abstract: ABSTRACT Introduction: Superficial infections involving the skin and mucosa are the most common fungal disease in humans. Fungi can also produce invasive infections (IFI), which are increasing in incidence among the growing population of immunocompromised… read more here.
Keywords: novel antifungal; antifungal agents; activity; review ... See more keywords
Modes-of-action of antifungal compounds: Stressors and (target-site-specific) toxins, toxicants, or Toxin-stressors.
Sign Up to like & getrecommendations! Published in 2023 at "Microbial biotechnology"
DOI: 10.1111/1751-7915.14242
Abstract: Fungi and antifungal compounds are relevant to the United Nation's Sustainable Development Goals. However, the modes-of-action of antifungals-whether they are naturally occurring substances or anthropogenic fungicides-are often unknown or are misallocated in terms of their… read more here.
Keywords: modes action; antifungal compounds; toxin; action ... See more keywords
A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus
Sign Up to like & getrecommendations! Published in 2021 at "mSphere"
DOI: 10.1128/msphere.00539-21
Abstract: Fungal infections caused by molds have the highest mortality rates of human fungal infections. These devastating infections are hard to treat and available antifungal drugs are often not effective. ABSTRACT Treatment of invasive mold infections… read more here.
Keywords: throughput; throughput screening; antifungal compounds; fungal infections ... See more keywords
Editorial: Antifungal Resistance: From Molecular to Global Issues
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.867398
Abstract: Efficient antifungal compounds to be applied in the clinics or in agriculture are becoming rare, as resistance is increasing in the targeted populations. The case of the sterol demethylation inhibitors is particular, as this type… read more here.
Keywords: resistance; antifungal resistance; antifungal compounds; resistance molecular ... See more keywords
Polyenic Antibiotics and Other Antifungal Compounds Produced by Hemolytic Streptomyces Species
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315045
Abstract: Streptomyces are of great interest in the pharmaceutical industry as they produce a plethora of secondary metabolites that act as antibacterial and antifungal agents. They may thrive on their own in the soil, or associate… read more here.
Keywords: hemolytic streptomyces; polyenic antibiotics; antifungal compounds; produced hemolytic ... See more keywords
In Silico Evaluation of Antifungal Compounds from Marine Sponges against COVID-19-Associated Mucormycosis
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20030215
Abstract: The world is already facing the devastating effects of the SARS-CoV-2 pandemic. A disseminated mucormycosis epidemic emerged to worsen this situation, causing havoc, especially in India. This research aimed to perform a multitargeted docking study… read more here.
Keywords: compounds marine; antifungal compounds; marine sponges; mucormycosis ... See more keywords
LC-HRMS/MS-Based Metabolomics Approaches Applied to the Detection of Antifungal Compounds and a Metabolic Dynamic Assessment of Orchidaceae
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227937
Abstract: The liquid chromatography–mass spectrometry (LC-MS)-based metabolomics approach is a powerful technology for discovering novel biologically active molecules. In this study, we investigated the metabolic profiling of Orchidaceae species using LC-HRMS/MS data combined with chemometric methods… read more here.
Keywords: antifungal compounds; orchidaceae; metabolomics approaches; based metabolomics ... See more keywords
Group I Intron as a Potential Target for Antifungal Compounds: Development of a Trans-Splicing High-Throughput Screening Strategy
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28114460
Abstract: The search for safe and efficient new antifungal compounds for agriculture has led to more efforts in finding new modes of action. This involves the discovery of new molecular targets, including coding and non-coding RNA.… read more here.
Keywords: group intron; antifungal compounds; throughput screening; group ... See more keywords