Antifungal drug shortage in India amid an increase in invasive fungal functions during the coronavirus disease 2019 (COVID-19) pandemic
Sign Up to like & getrecommendations! Published in 2021 at "Infection Control and Hospital Epidemiology"
DOI: 10.1017/ice.2021.426
Abstract: Ashitha B. Arun1, MohammadMehedi Hasan2 , Sudhan Rackimuthu3, Irfan Ullah4, Tanveer Mir5 and Anwesha Saha6 1St Joseph’s College, Bangalore, India, 2Department of Biochemistry and Molecular Biology, Faculty of Life Science, Mawlana Bhashani Science and Technology… read more here.
Keywords: india amid; antifungal drug; amid increase; drug shortage ... See more keywords
Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads.
Sign Up to like & getrecommendations! Published in 2021 at "Scientific reports"
DOI: 10.1038/s41598-021-00349-9
Abstract: Aspergillus fumigatus is a fungal pathogen whose effects can be debilitating and potentially fatal in immunocompromised patients. Current drug treatment options for this infectious disease are limited to just a few choices (e.g. voriconazole and… read more here.
Keywords: aspergillus fumigatus; acetohydroxyacid synthase; drug; antifungal drug ... See more keywords
Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical implications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac161
Abstract: Abstract The increasing incidence and changing epidemiology of invasive fungal infections continue to present many challenges to their effective management. The repertoire of antifungal drugs available for treatment is still limited although there are new… read more here.
Keywords: fungal pathogens; detection; resistance; antifungal drug ... See more keywords
Antifungal Drug Concentration Impacts the Spectrum of Adaptive Mutations in Candida albicans
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msad009
Abstract: Abstract Invasive fungal infections are a leading global cause of human mortality. Only three major classes of antifungal drugs are widely used, and resistance to all three classes can arise rapidly. The most widely prescribed… read more here.
Keywords: drug concentration; concentration impacts; antifungal drug; drug ... See more keywords
Changes in the distribution of colonising and infecting Candida spp. isolates, antifungal drug consumption and susceptibility in a French intensive care unit: A 10‐year study
Sign Up to like & getrecommendations! Published in 2017 at "Mycoses"
DOI: 10.1111/myc.12661
Abstract: Monitoring fungal ecology and resistance to antifungal agents within intensive care units (ICU) is essential for the management of invasive fungal infections. Therefore, a retrospective descriptive study was carried in the ICU of Nimes University… read more here.
Keywords: antifungal agents; candida; antifungal drug; consumption ... See more keywords
Systemic antifungal drug use in Belgium—One of the biggest antifungal consumers in Europe
Sign Up to like & getrecommendations! Published in 2019 at "Mycoses"
DOI: 10.1111/myc.12912
Abstract: Reports on the consumption of systemic antifungal drugs on a national level are scarce although of high interest to compare trends and the associated epidemiology in other countries and to assess the need for antifungal… read more here.
Keywords: systemic antifungal; drug use; antifungal drug; use belgium ... See more keywords
Antifungal drug price increases in the United States, 2000–2019
Sign Up to like & getrecommendations! Published in 2022 at "Mycoses"
DOI: 10.1111/myc.13486
Abstract: Antifungal drugs treat a variety of conditions, ranging from localised dermatologic disease to life‐threatening systemic infections. Some common antifungal drugs experienced large price increases in recent years, however, factors contributing to these price increases are… read more here.
Keywords: drug price; price; antifungal drug; increases united ... See more keywords
On Fruits and Fungi: A Risk of Antifungal Usage in Food Storage and Distribution in Driving Drug Resistance in Candida auris
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.00739-22
Abstract: The continuous emergence of antifungal drug resistance is a mounting concern for the treatment of fungal infections worldwide. While many pathogenic fungi exhibit some level of antifungal drug resistance, the identification of Candida auris has… read more here.
Keywords: candida auris; resistance; antifungal drug; drug ... See more keywords
Advanced Vesicular Systems for Antifungal Drug Delivery
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02357-y
Abstract: Fungal infections are considered one of the most serious conditions as their occurrence has increased lately. Fungi like Candida, Fusarium, and Aspergillus species mostly affect immunocompromised patients as they are considered opportunistic pathogens. These infections… read more here.
Keywords: advanced vesicular; drug delivery; antifungal drug; fungal infections ... See more keywords
Antimycotic Drugs and their Mechanisms of Resistance to Candida Species.
Sign Up to like & getrecommendations! Published in 2021 at "Current drug targets"
DOI: 10.2174/1389450122666210719124143
Abstract: Fungal infections have shown an upsurge in recent decades, which is mainly because of the increasing number of immunocompromised patients and the occurrence of invasive candidiasis has been found to be 7-15 fold greater than… read more here.
Keywords: drug; fungal infections; antifungal drug; resistance ... See more keywords
Antifungal Drug Resistance: An Emergent Health Threat
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041063
Abstract: Fungal infections, named mycosis, can cause severe invasive and systemic diseases that can even lead to death. In recent years, epidemiological data have recorded an increase in cases of severe fungal infections, caused mainly by… read more here.
Keywords: antifungal drug; fungal infections; drug; health threat ... See more keywords