The discovery of novel antifungal phenylpyridines derivatives based on CYP53 binding model.
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DOI: 10.2139/ssrn.4090734
Abstract: Benzoates as toxic intermediate are naturally produced by fungal intracellular metabolism, and CYP53 can specific transform the substrates. In the study, we constructed the CYP53 homology model and analyzed the corresponding active region. At the… read more here.
Keywords: antifungal phenylpyridines; discovery novel; phenylpyridines derivatives; novel antifungal ... See more keywords