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Published in 2018 at "Infectious Diseases"
DOI: 10.1080/23744235.2017.1396621
Abstract: Abstract Background: Consensus has yet to be reached regarding secondary prophylaxis in allogeneic hematopoietic stem cell transplantation (HSCT) with a complete resolution of invasive aspergillosis (IA) confirmed by chest computed tomography (CT). Methods: We retrospectively… read more here.
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Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dky550
Abstract: BACKGROUND We evaluated the incidence of proven/probable invasive aspergillosis (IA) and the role of antifungal prophylaxis (AP) in a 'real-life' setting of patients with AML receiving intensive consolidation therapy. METHODS Cases of IA, observed during… read more here.
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Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.932
Abstract: Fungal infections in patients with hematologic malignancies are associated with high mortality. Primary antifungal prophylaxis has been shown to be a more effective strategy than treating a documented infection. This retrospective analysis aims to compare… read more here.
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Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.017
Abstract: Abstract Background IMI have high mortality among LTR. Prevention is critical. Data supporting guideline-recommended three-tiered approach to antifungal prophylaxis based on risk for IMI are lacking. Methods Retrospective study of 534 adult LTR at the… read more here.
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Published in 2021 at "Transplantation"
DOI: 10.1097/tp.0000000000003717
Abstract: Supplemental Digital Content is available in the text. Background. Lung transplantation is an important treatment option for various end-stage lung diseases. However, survival remains limited due to graft rejection and infections. Despite that fungal infections… read more here.
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Published in 2019 at "Clinical Transplantation"
DOI: 10.1111/ctr.13691
Abstract: There is a lack of high‐level evidence identifying meaningful outcomes and the place in therapy for systemic perioperative antifungal prophylaxis (ppx) in pancreas transplant recipients. As our program does not routinely utilize systemic perioperative antifungal… read more here.
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Published in 2019 at "Mycoses"
DOI: 10.1111/myc.13020
Abstract: Posaconazole is used to prevent invasive fungal infections (IFIs) in patients with haematologic malignancy. In this study, we compared plasma posaconazole concentrations (PPCs) and the incidence of breakthrough IFIs between patients with haematologic malignancy receiving… read more here.
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Published in 2020 at "Mycoses"
DOI: 10.1111/myc.13130
Abstract: Candidaemia is an important infectious complication for haematological malignancy patients. Antifungal prophylaxis reduces the incidence of candidaemia but may be associated with breakthrough candidaemia. read more here.
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Published in 2020 at "Mycoses"
DOI: 10.1111/myc.13232
Abstract: Patients undergoing allogeneic stem cell transplantation (aSCT) are at high risk to develop an invasive fungal disease (IFD). Optimisation of antifungal prophylaxis strategies may improve patient outcomes and reduce treatment costs. read more here.
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Published in 2022 at "Mycoses"
DOI: 10.1111/myc.13495
Abstract: Patients undergoing induction/reinduction chemotherapy for haematologic malignancies (HM) are at risk for invasive fungal infections (IFIs). In 2015, Duke University Hospital (DUH) implemented a new standardised fungal prophylaxis protocol for adult patients undergoing induction chemotherapy… read more here.