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   Articles with "antigen" as a keyword



Comparison of Home Antigen Testing With RT-PCR and Viral Culture During the Course of SARS-CoV-2 Infection.

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recommendations! Published in 2022 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2022.1827

Abstract: Importance As self-collected home antigen tests become widely available, a better understanding of their performance during the course of SARS-CoV-2 infection is needed. Objective To evaluate the diagnostic performance of home antigen tests compared with… read more here.

Keywords: antigen test; home antigen; antigen; infection ... See more keywords

Insights Into Cardiovascular Risks of Chimeric Antigen Receptor T-Cell Therapy-From Peril to Promise.

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recommendations! Published in 2024 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2024.37157

Abstract: The development of autologous chimeric antigen receptor (CAR) T-cell therapy is a momentous breakthrough as the first personalized, genetically engineered living therapy. Reported initially at the bench in 1987, 1 over the span of the… read more here.

Keywords: receptor; cell therapy; antigen; car ... See more keywords

Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14446

Abstract: Mtb8.4, a secretory T‐cell antigen of Mycobacterium tuberculosis, is important for providing an antigen‐specific immune response. In this study, we showed Mtb8.4 to have both heme‐binding and fibril‐forming properties, using experimental and in silico methods.… read more here.

Keywords: heme; heme binding; mtb8 heme; mtb8 ... See more keywords

Intein-based modular chimeric antigen receptor platform for specific CD19/CD20 co-targeting.

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recommendations! Published in 2025 at "Molecular oncology"

DOI: 10.1002/1878-0261.70146

Abstract: Development of chimeric antigen receptor T-cell therapy has revolutionized the treatment of B-cell malignancies, although challenges such as antigen escape and tumor heterogeneity often decrease treatment success. Modular CARs targeting multiple antigens have been proposed… read more here.

Keywords: antigen; chimeric antigen; cd19 cd20; antigen receptor ... See more keywords

Lewis b antigen is a common ligand for genogroup I norovirus strains

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recommendations! Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13455

Abstract: Noroviruses are major causative agents of nonbacterial acute gastroenteritis in humans. Ten genogroups of noroviruses have been identified to date, among which genogroup I (GI) and genogroup II (GII) noroviruses are major pathogens for humans.… read more here.

Keywords: antigen common; lewis antigen; common ligand; genogroup ... See more keywords

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

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recommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.70167

Abstract: We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG). These findings provide insight into… read more here.

Keywords: therapy; antigen; myasthenia gravis; cell ... See more keywords

Retardation of Antigen Release from DNA Hydrogel Using Cholesterol‐Modified DNA for Increased Antigen‐Specific Immune Response

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recommendations! Published in 2017 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201700355

Abstract: Our previous study indicates that cationization of an antigen is effective for sustained release of both immunostimulatory DNA containing unmethylated cytosine-phosphate-guanine (CpG) dinucleotides, or CpG DNA, and antigen from a DNA hydrogel. Another approach to… read more here.

Keywords: cholesterol modified; dna; dna hydrogel; antigen ... See more keywords

Conjugation-Free Multilamellar Protein-Lipid Hybrid Vesicles for Multifaceted Immune Responses.

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recommendations! Published in 2021 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202101239

Abstract: Various lipid-based nanocarriers have been developed for the co-delivery of protein antigens with immunological adjuvants. However, their in vivo potency in vaccine delivery is limited by structural instability, which causes off-target delivery and low cross-presentation… read more here.

Keywords: protein; protein antigens; delivery; free multilamellar ... See more keywords

Tissue‐Targeted Drug Delivery Strategies to Promote Antigen‐Specific Immune Tolerance

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202202238

Abstract: During autoimmunity or organ transplant rejection, the immune system attacks host or transplanted tissue, causing debilitating inflammation for millions of patients. There is no cure for most of these diseases. Further, available therapies modulate inflammation… read more here.

Keywords: immune tolerance; tolerance; drug delivery; antigen specific ... See more keywords

A Novel Signal‐On Electrochemiluminescence Immunosensor for the Detection of NSCLC Antigen Biomarker Based on New Co‐Reaction Accelerators

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202202287

Abstract: Non‐small cell lung cancer (NSCLC) is the most common type of lung cancer with substantial morbidity and mortality. Herein, a new signal‐on electrochemiluminescence (ECL) immunosensor based on multiple amplification strategies is constructed for ultrasensitive detection… read more here.

Keywords: antigen; immunosensor; detection; nimn ldh ... See more keywords

Engineered Curli Nanofilaments as a Self-Adjuvanted Antigen Delivery Platform.

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recommendations! Published in 2023 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202300224

Abstract: Proteinaceous nanoparticles constitute efficient antigen delivery systems in vaccine formulations due to their size and repetitive nature that mimic most invading pathogens and promote immune activation. Nonetheless, the co-administration of an adjuvant with subunit nanovaccines… read more here.

Keywords: self adjuvanted; delivery platform; antigen; antigen delivery ... See more keywords