Unraveling the Hook Effect: A Comprehensive Study of High Antigen Concentration Effects in Sandwich Lateral Flow Immunoassays
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DOI: 10.1021/acs.analchem.0c03740
Abstract: Sandwich lateral flow immunoassays (LFIAs) are limited at high antigen concentrations by the hook effect, leading to a contradictory decrease in the test line (T) intensity and false-negative results. The hook effect is mainly associated… read more here.
Keywords: hook effect; high antigen; antigen; antigen concentration ... See more keywords