Evidence for an involvement of the ubiquitin‐like modifier ISG15 in MHC class I antigen presentation
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.202048646
Abstract: The IFN stimulated gene 15 (ISG15) encodes a 15‐kDa ubiquitin‐like protein, that is induced by type I IFNs and is conjugated to the bulk of newly synthesized polypeptides at the ribosome. ISG15 functions as an… read more here.
Keywords: presentation; ubiquitin like; isg15; antigen presentation ... See more keywords
Tumor Antigen Loaded Nanovaccine Induced NIR-Activated Inflammation for Enhanced Antigen Presentation During Immunotherapy of Tumors.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205193
Abstract: Although anticancer vaccines have achieved certain effects in early clinical practice, T cell immunity as the most common responsive pattern of anticancer vaccines is still limited by unsatisfied tumor recognition and inhibition efficiency. As the… read more here.
Keywords: cell; presentation; antigen presentation; tumor ... See more keywords
Virus-Mediated Suppression of the Antigen Presentation Molecule MR1
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.02.017
Abstract: SUMMARY The antigen-presenting molecule MR1 presents microbial metabolites related to vitamin B2 biosynthesis to mucosal-associated invariant T cells (MAIT cells). Although bacteria and fungi drive the MR1 biosynthesis pathway, viruses have not previously been implicated… read more here.
Keywords: mr1; antigen; antigen presentation; cell ... See more keywords
Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.108861
Abstract: Summary T cells form immunological synapses with professional antigen-presenting cells (APCs) resulting in T cell activation and the acquisition of peptide antigen-MHC (pMHC) complexes from the plasma membrane of the APC. They thus become APCs… read more here.
Keywords: presentation cells; antigen presentation; antigen; cell ... See more keywords
Four pathways of CD1 antigen presentation to T cells.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2017.07.013
Abstract: CD1a, CD1b, CD1c and CD1d proteins migrate through distinct subcellular compartments of antigen presenting cells and so can be considered to take four separate pathways leading to display of lipid antigens to T cell receptors.… read more here.
Keywords: presentation cells; cd1 antigen; four pathways; pathways cd1 ... See more keywords
Antigen presentation by dendritic cells for B cell activation.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2019.04.003
Abstract: B cells are efficiently activated by antigens presented on cell membranes, which provide opportunity for receptor cross-linking and antigen capture. The two main cell types implicated in native antigen presentation to B cells are follicular… read more here.
Keywords: dendritic cells; antigen presentation; antigen; presentation dendritic ... See more keywords
Antigen presentation by MHC-E: a putative target for vaccination?
Sign Up to like & getrecommendations! Published in 2022 at "Trends in immunology"
DOI: 10.1016/j.it.2022.03.002
Abstract: The essentially monomorphic human antigen presentation molecule HLA-E is an interesting candidate target to enable vaccination irrespective of genetic diversity. Predictive HLA-E peptide-binding motifs have been refined to facilitate HLA-E peptide discovery. HLA-E can accommodate… read more here.
Keywords: presentation; vaccination; antigen presentation; target ... See more keywords
Inhibition of antigen presentation by Brucella: many more than many ways.
Sign Up to like & getrecommendations! Published in 2019 at "Microbes and infection"
DOI: 10.1016/j.micinf.2018.12.004
Abstract: Brucella infection activates the immune system and favors the differentiation of CD4+ and CD8+ T cells. To persist during a long time inside macrophages evading immune surveillance of these T cells the pathogen must exploit… read more here.
Keywords: presentation brucella; antigen presentation; brucella many; antigen ... See more keywords
Effect of Phosphate Ion on the Structure of Lumazine Synthase, an Antigen Presentation System From Bacillus anthracis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.10.013
Abstract: Lumazine synthase (LS) is an oligomeric enzyme involved in the biosynthesis of riboflavin in microorganisms, fungi, and plants. LS has become of significant interest to biomedical science because of its critical biological role and attractive… read more here.
Keywords: lumazine synthase; bacillus anthracis; antigen presentation; structure ... See more keywords
Glutamine Metabolism-Regulated Nanoparticles to Enhance Chemoimmunotherapy by Increasing Antigen Presentation Efficiency.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c21417
Abstract: Although the strategies to induce dendritic cells (DCs) maturation and promote their antigen presentation can stimulate the tumor immune response, the endogenous deficiency and immunosuppression of DCs reduce antigen utilization, which limits antigen presentation efficiency… read more here.
Keywords: presentation efficiency; tumor; antigen presentation; presentation ... See more keywords
Hypoxia-Triggered Transforming Immunomodulator for Cancer Immunotherapy via Photodynamically Enhanced Antigen Presentation of Dendritic Cell.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.8b07045
Abstract: A key factor for successful cancer immunotherapy (CIT) is the extent of antigen presentation by dendritic cells (DCs) that phagocytize tumor-associated antigens (TAA) in the tumor site and migrate to tumor draining lymph nodes (TDLN)… read more here.
Keywords: antigen presentation; cancer immunotherapy; tumor;